34042
雷复尼特
PESTANAL®, analytical standard
别名:
3′-氯-4′-(4-氯苯氧基)-3,5-二碘水杨酰苯胺
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关于此项目
经验公式（希尔记法）:
C19H11Cl2I2NO3
化学文摘社编号:
分子量:
626.01
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
产品线
PESTANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
agriculture
environmental
包装形式
neat
SMILES字符串
Oc1c(I)cc(I)cc1C(=O)Nc2ccc(Oc3ccc(Cl)cc3)c(Cl)c2
InChI
1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)
InChI key
NEMNPWINWMHUMR-UHFFFAOYSA-N
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相关类别
一般描述
Rafoxanide is a halogenated salicylanilide and an anthelmintic agent. It is widely used against fasciolosis and haemonchosis in sheep and cattle. It also finds applications as an adulticide for Fasciola hepatica and Fasciola gigantica.
应用
Rafoxanide may be used as a reference standard in the determination of rafoxanide in plasma and tissue samples using high-performance liquid chromatography (HPLC) coupled with an ultraviolet detector and thermospray − mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
其他说明
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
法律信息
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Antonio Di Grazia et al.
Cancers, 12(5) (2020-05-28)
Colorectal cancer (CRC) is a major cause of cancer-related death in the world. Emerging evidence suggests that the clinical success of conventional chemotherapy does not merely rely on cell toxicity, but also results from the restoration of tumor immune surveillance.
Determination of rafoxanide in plasma using high performance liquid chromatography (HPLC) and in tissue using HPLC-thermospray mass spectrometry
Blanchflower J W, et al.
Journal of Liquid Chromatography, 13(8), 1595-1609 (1990)
H Ram et al.
Veterinary research communications, 31(6), 719-723 (2007-02-20)
A trial using albendazole, albendazole plus rafoxanide combination, ivermectin and doramectin was conducted in Pashmina goats having history of fenbendazole resistance to Haemonchus spp. and maintained at high altitude (>2350 m above sea level). Day 0 infection level was variable
J H Boersema et al.
Veterinary parasitology, 68(4), 383-388 (1997-03-01)
A survey was conducted on the occurrence of anthelmintic resistance of trichostrongylids on commercial sheep farms in the highveld of Zimbabwe. On ten farms the efficacy of fenbendazole, levamisole and rafoxanide was tested by a faecal egg count reduction test.
C P Swarnkar et al.
Tropical animal health and production, 33(4), 305-312 (2001-07-28)
Monitoring anthelmintic resistance in strongyle nematodes by the faecal egg count reduction test and a commercial larval development assay on an organized sheep farm in the semi-arid area of Rajasthan revealed the emergence of resistance to benzimidazoles and rafoxanide and
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