34093
克罗散泰
PESTANAL®, analytical standard
别名:
N-[5-氯-4-(4-氯-α-氰基苄基)-2-甲基苯基]-2-羟基-3,5-二碘苯甲酰胺, 氯氰碘柳胺
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经验公式（希尔记法）:
C22H14Cl2I2N2O2
化学文摘社编号:
分子量:
663.07
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
260-967-1
MDL number:
InChI key
JMPFSEBWVLAJKM-UHFFFAOYSA-N
InChI
1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)
SMILES string
Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c3cc(I)cc(I)c3O
grade
analytical standard
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
agriculture
environmental
format
neat
storage temp.
2-8°C
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Closantel belongs to the salicylanilide class of anthelmintics, that can extensively bind to the plasma albumin. It can be effectively used against, a vast range of blood feeding internal parasites.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 4
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Quantitative determination of Closantel residues in milk by high-performance liquid chromatography with fluorescence detection
Stove.G, et al.
Journal of Chromatography A, 846, 383-386 (1999)
Closantel toxicosis in kid goats.
R Ecco et al.
The Veterinary record, 159(17), 564-566 (2006-10-24)
Yumi Kumagai et al.
Infection and immunity, 74(9), 5014-5022 (2006-08-24)
Ehrlichia chaffeensis, the etiologic agent of human monocytic ehrlichiosis, replicates in early endosomes by avoiding lysosomal fusion in monocytes and macrophages. In E. chaffeensis we predicted three pairs of putative two-component regulatory systems (TCSs) designated PleC-PleD, NtrY-NtrX, and CckA-CtrA based
Hanwen Sun et al.
Journal of chromatography. A, 1175(2), 227-233 (2007-11-16)
A liquid chromatographic-electrospray ionisation-tandem mass spectrometry method (LC-ESI-MS/MS) with solid extraction was developed and validated for the detection and determination of closantel residues in bovine tissues and milk. An acetonitrile-acetone mixture (80:20, v/v) was used for one-stage extraction of closantel
F A Almeida et al.
Parasitology international, 59(4), 622-625 (2010-10-05)
The objective of this study was to determine the level of resistance of Haemonchus contortus and Trichostrongylus colubriformis in sheep to levamisole, albendazole, ivermectin, moxidectin, closantel and trichlorfon. The parasites were isolated from sheep naturally infected by gastrointestinal nematodes and
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