34176
奥芬达唑
VETRANAL®, analytical standard
别名:
5-(苯亚磺酰)-苯并咪唑-2-氨基甲酸甲酯
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关于此项目
经验公式（希尔记法）:
C15H13N3O3S
化学文摘社编号:
分子量:
315.35
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
258-714-5
MDL number:
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
COC(=O)Nc1nc2cc(ccc2[nH]1)S(=O)c3ccccc3
InChI
1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)
InChI key
BEZZFPOZAYTVHN-UHFFFAOYSA-N
General description
Oxfendazole is a benzimidazole anthelmintic drug, effective against cysticercosis, echinococcosis and fasciolosis.
Oxfendazole is a member of benzimidazole group of anthelmintics.
Application
Oxfendazole may be used as an analytical reference standard for the determination of the analyte in bovine liver by liquid chromatography method.
Oxfendazole may be used as a reference standard in the determination of oxfendazole in pharmaceutical preparations using reversed-phase high-performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Yasuaki Dewa et al.
Archives of toxicology, 81(9), 647-654 (2007-03-07)
The effect of oxfendazole (OX), a benzimidazole anthelmintic, on hepatic gene expression was investigated in the liver of rats as a preliminary study to elucidate the possible mechanism of its non-genotoxic hepatocarcinogenesis. The liver from a male F344/N rat given
Jihei Nishimura et al.
Archives of toxicology, 84(2), 143-153 (2009-12-25)
To clarify whether enzymatically modified isoquercitrin (EMIQ) or melatonin (MLT) supplementation reduces oxidative stress-mediated hepatocellular tumor-promoting effect of oxfendazole (OX), a benzimidazole anthelmintic, male rats were administered a single intraperitoneal injection of N-diethylnitrosamine (DEN) and were fed a diet containing
Chemotherapy of Gastrointestinal Helminths.
Handbook of Experimental Pharmacology, 77, 111-114 (2012)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 34176-100MG | 04061826754498 |