Merck
CN
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文件

34213

Supelco

帕珠沙星

VETRANAL®, analytical standard

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经验公式（希尔记法）:
C16H15FN2O4
CAS号:
127045-41-4
分子量:
318.30
MDL编号:
MFCD00865012
PubChem化学物质编号:
329754899
NACRES:
NA.24

等级

analytical standard

质量水平

100

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

clinical testing

格式

neat

储存温度

2-8°C

SMILES字符串

C[C@H]1COc2c3N1C=C(C(O)=O)C(=O)c3cc(F)c2C4(N)CC4

InChI

1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1

InChI key

XAGMUUZPGZWTRP-ZETCQYMHSA-N

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相关类别

一般描述

Chemical structure: quinolone
Pazufloxacin is a fluoroquinolone antibiotic, which shows broad spectrum activity in anti-infective chemotherapy.

应用

Pazufloxacin may be used as a reference standard in the determination of pazufloxacin in serum and plasma samples using high performance liquid chromatography coupled with fluorescence detector (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 + H312 + H332

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

分析证书(COA)

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T1503
货号
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包装规格/数量

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Shinzaburo Minami et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 122(2), 161-178 (2003-08-02)
Pazufloxacin mesilate (PZFX: Pasil INJECTION, Pazucross INJECTION) is a novel injectable quinolone antibiotic that was discovered by Toyama Chemical Co., Ltd. and codeveloped by Toyama Chemical Co. Ltd. and Mitsubishi Pharma Corporation. Laboratory studies indicated that PZFX reached high plasma
Naoyuki Miyashita et al.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 26(5), 411-417 (2020-02-23)
Legionella species are consistently identified as some of the most common causative agents of severe community-acquired pneumonia (CAP) or nosocomial pneumonia. Although the number of reported Legionella infection cases is gradually increasing in Japan, most cases are diagnosed by a
First liquid chromatography method for the simultaneous determination of levofloxacin, pazufloxacin, gatifloxacin, moxifloxacin and trovafloxacin in human plasma.
Sousa J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 930, 104-111 (2013)
A P Johnson
Current opinion in investigational drugs (London, England : 2000), 1(1), 52-57 (2001-03-16)
Toyama Chemical Co Ltd is developing pazufloxacin (T-3761), an orally active synthetic quinolone antibiotic, which is awaiting registration following successful clinical trials that demonstrated its pharmacological similarities to tosufloxacin (Toyama Chemical Co) with respect to clinical efficacy, adverse effects and
Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection.
Watabe S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 878(19), 1555-1561 (2010)
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