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Merck
CN

37019

阿托品

analytical standard

别名:

(8-甲基-8-氮杂双环[3.2.1]辛-3-基) endo-(+/-)-α-(羟甲基)苯乙酸酯, 莨菪碱, 龙葵碱

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关于此项目

经验公式(希尔记法):
C17H23NO3
化学文摘社编号:
分子量:
289.37
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-104-8
Beilstein/REAXYS Number:
91260
MDL number:
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grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

InChI key

RKUNBYITZUJHSG-SPUOUPEWSA-N

Gene Information

General description

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
For the analysis of the phytotoxins.

Application

Atropine may be used as a reference standard for the determination of atropine in:
  • Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
  • Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
  • Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
  • Plant materials by liquid-liquid extraction and EXtrelut® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:
  • Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
  • Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
  • Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
  • Plant materials by liquid-liquid extraction and EXtrelut® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Biochem/physiol Actions

位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。

Preparation Note

Dried down, ~100μg/mL after reconstitution with 1 mL of water

Analysis Note

purity : ≥96.0% (HPLC)

Legal Information

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Are tropane alkaloids present in organic foods? Detection of scopolamine and atropine in organic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
<BIG>Cirlini M, et al.</BIG>
Food Chemistry, 239, 141-147 (2018)
High-throughput screening for drugs of abuse and pharmaceutical drugs in hair by liquid-chromatography-high resolution mass spectrometry (LC-HRMS).
<BIG>Odoardi S, et al.</BIG>
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 133, 302-310 (2017)
Isolation of atropine and scopolamine from plant material using liquid-liquid extraction and EXtrelut columns
<BIG>Sramska P, et al.</BIG>
Journal of Chromatography. B, Biomedical Sciences and Applications, 1043, 202-208 (2017)