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Merck
CN

37919

Supelco

脱水四环素 盐酸盐

VETRANAL®, analytical standard

别名:

(4S,4aS,12aS)-4-(二甲基氨基)-1,4,4a,5,12,12a-六氢-3,10,11,12a-四羟基-6-甲基-1,12-二氧-2-萘并羧酰胺 单盐酸盐

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关于此项目

经验公式（希尔记法）:
C22H22N2O7 · HCl
化学文摘社编号:
13803-65-1
分子量:
462.88
Beilstein:
4228856
MDL编号:
MFCD00151453
UNSPSC代码:
41116107
PubChem化学物质编号:
329755727
NACRES:
NA.24

主要文件

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等级

analytical standard

质量水平

100

Agency

EPA 1694

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

储存条件

under inert gas

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

clinical testing

包装形式

neat

SMILES字符串

Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16-,22-;/m0./s1

InChI key

XBSQEFHDCDFNJU-WPJNXPDPSA-N

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相关类别

一般描述

脱水四环素(ATC)是盐酸四环素的降解产物，在动物育种中广泛用作抗生素。

应用

分析标准品可用于：
  • 通过太赫兹(THz)光谱-温度依赖性技术定量和定性分析抗生素、 盐酸四环素和其三种主要代谢产物。
  • 通过共振拉曼光谱技术同时分析药物制剂中的盐酸四环素及降解产物，研究应激诱导的药物稳定性。
  • 开发和验证液相色谱-串联质谱(LC-MS/MS)方法，测定蜂蜜样本中21种用作兽药的抗生素残留。
  • 通过液液微萃取(DLLME)及超高压液相色谱(UHPLC)-可调谐紫外检测(TUV)技术测定各种环境水样中的8种四环素抗生素。

其他说明

有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险声明

H302,H360D

危险分类

Acute Tox. 4 Oral - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL9210
BCCK3339
BCCJ1168
BCCG9640
BCCF4540

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. How can I dissolve anhydrotetracycline hydrochloride?

    Anhydrotetracycline hydrochloride can be dissolved in any of several different organic solvents:1.  Ethanol:  2 mg/mL2.  DMSO:  10 mg/mL3.  DMF:  10 mg/mL.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Susceptibility of Escherichia coli and Enterococcus faecium isolated from pigs and broiler chickens to tetracycline degradation products and distribution of tetracycline resistance determinants in E. coli from food animals
Sengelov G, et al.
Veterinary Microbiology, 95, 91-101 (2003)
Wyndham W Lathem et al.
Science (New York, N.Y.), 315(5811), 509-513 (2007-01-27)
Primary pneumonic plague is transmitted easily, progresses rapidly, and causes high mortality, but the mechanisms by which Yersinia pestis overwhelms the lungs are largely unknown. We show that the plasminogen activator Pla is essential for Y. pestis to cause primary
Jonathan W Kotula et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(13), 4838-4843 (2014-03-19)
The mammalian gut is a dynamic community of symbiotic microbes that interact with the host to impact health, disease, and metabolism. We constructed engineered bacteria that survive in the mammalian gut and sense, remember, and report on their experiences. Based
Christine R Whetstine et al.
Applied and environmental microbiology, 75(20), 6553-6558 (2009-08-25)
We developed a single-plasmid-based regulatable protein expression system for Borrelia burgdorferi. Expression of a target gene is driven by P(ost), a hybrid B. burgdorferi ospA-tetO promoter, from a recombinant B. burgdorferi plasmid constitutively expressing TetR. The system was tested using
Marta Gratacós-Cubarsí et al.
Journal of agricultural and food chemistry, 55(11), 4610-4616 (2007-05-10)
Tetracycline (TC) and 4-epitetracycline (4eTC) degradation, as well as anhydrotetracycline (ATC) and 4-epianhydrotetracycline (4eATC) formation, has been evaluated in thermally treated chicken breast, pig loin, and pig loin with added back-fat. Samples containing TC and 4eTC residues were submitted to
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