Merck
CN

42251

Supelco

芹菜素

analytical standard

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别名:
4 & # 8242;,5,7-三羟基黄酮, 5,7-二羟基-2-(4-羟基苯基)-4-苯并吡喃酮
Empirical Formula (Hill Notation):
C15H10O5
CAS号:
分子量:
270.24
Beilstein:
262620
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥99% (HPLC)

保质期

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

application(s)

food and beverages

格式

neat

储存温度

2-8°C

SMILES string

Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H

InChI key

KZNIFHPLKGYRTM-UHFFFAOYSA-N

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此商品
SMB007021040683178278
Apigenin analytical standard

Supelco

42251

芹菜素

Apigenin ≥97% (TLC), from citrus

Sigma-Aldrich

SMB00702

芹菜素

Apigenin United States Pharmacopeia (USP) Reference Standard

USP

1040683

芹菜素

Apigenin Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 µM).

Sigma-Aldrich

178278

Apigenin

assay

≥99% (HPLC)

assay

≥97% (TLC)

assay

-

assay

≥98% (HPLC)

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

food and beverages

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

pharmaceutical (small molecule)

application(s)

-

format

neat

format

-

format

neat

format

-

一般描述

黄酮类化合物属于多酚类化合物。在抑制肿瘤生长和化学预防等生物活性中起关键作用。芹菜素是一种植物类黄酮,多用于抑制鸟氨酸脱羧酶活性和皮肤肿瘤。

应用

LC-ESI-MS/MS 可作为内标物,用于测定大鼠血液和尿液中的飞燕草苷及其代谢产物。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。

生化/生理作用

一种植物类黄酮,研究发现它通过在G2/M阶段阻止细胞周期来抑制细胞增殖。通过细胞周期停滞和诱导凋亡来抑制生长似乎与p53的诱导有关。通过抑制蛋白激酶C和由此导致的癌基因表达抑制来抑制PMA介导的肿瘤促进。研究还报道了抑制拓扑异构酶ⅰ催化的脱氧核糖核酸再连接和增强间隙连接细胞间通讯。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3


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Determination of the metabolite content of Brassica juncea cultivars using comprehensive two-dimensional liquid chromatography coupled with a photodiode array and mass spectrometry detection
Arena K, et al.
Molecules (Basel), 25(5), 1235-1235 (2020)
Lingling Pang et al.
International journal of clinical and experimental pathology, 12(10), 3700-3709 (2020-01-15)
The purpose of this study was to investigate the anti-inflammatory potential of the natural flavonoid apigenin to mitigate the airway inflammation in asthmatic mice exposed to particulate matter (PM) 2.5, and examine the possible mechanisms involved. BALB/c mice were sensitized
Eric Jaziel Medrano-Sánchez et al.
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The genus Cecropia is used in the traditional medicine of Tabasco, Mexico, in diabetes and hypertension treatments, mainly without distinction of the species. This contribution aimed to carry out the metabolic analysis and Proton Nuclear Magnetic Resonance (1H-NMR) spectroscopy-based fingerprinting
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential.
Caltagirone S
International Journal of Cancer. Journal International Du Cancer, 87(4), 595-600 (2000)
Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry.
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Journal of Agricultural and Food Chemistry, 52(12), 3708-3712 (2004)

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