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Merck
CN

42635

人参皂荚 Rb3

analytical standard

别名:

人参皂甙 RB3, （3β,12β）-3-[（2-O-β-D-葡糖吡喃糖基-β-D-吡喃葡萄糖基）氧基] -12-羟基达玛-24-en-20-基 6-O-β-D-吡喃吡喃糖基-β-D-吡喃葡萄糖苷

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关于此项目

经验公式（希尔记法）:
C53H90O22
化学文摘社编号:
68406-26-8
分子量:
1079.27
NACRES:
NA.24
PubChem Substance ID:
329756253
UNSPSC Code:
85151701
MDL number:
MFCD10566396

主要文件

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产品名称

人参皂荚 Rb3, analytical standard

InChI key

NODILNFGTFIURN-USYOXQFSSA-N

SMILES string

C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)[C@@H]3[C@H](O)C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)[C@@H]6CC[C@@]45C

InChI

1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCK2685
BCCF1032
BCCF1465
BCCB0804
BCBZ6845

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Jihong Cui et al.
Journal of psychopharmacology (Oxford, England), 26(5), 697-713 (2011-09-29)
Total ginsenosides have been shown to have therapeutic actions as antidepressants. We report a major active ingredient of total ginsenosides, the ginsenoside Rb3 (Rb3), which may have antidepressant-like effects. Using the forced swim test, tail suspension test, and learned helplessness
Shan Jiang et al.
Journal of ethnopharmacology, 133(2), 914-916 (2010-10-26)
To investigate the effect of ginsenoside Rb(3) on synaptic transmission after oxygen-glucose deprivation in vitro. The population spike (PS) was recorded in the stratum pyramidale of mouse hippocampal slices using extracellular recordings. Ginsenoside Rb(3) depressed the basal synaptic transmission, which
Qi Tao Bu et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 8(5), 934-941 (2012-06-30)
As one of the main active component of protopanaxdiol type ginsenosides, ginsenoside Rb(3) is rarely reported in the treatment of diabetes. The anti-diabetic activity of ginsenoside Rb(3) was investigated in a model of alloxan-induced diabetic mice in the present study.
Kejiang He et al.
Chemical & pharmaceutical bulletin, 53(2), 177-179 (2005-02-03)
A dammarane glycoside, designated compound Mx (C-Mx), was isolated from the hydrolysate of 20(S)-protopanaxadiol type ginsenosides containing G-Rb(3) from Panax notoginseng leaves with crude snailase. Its chemical structure was elucidated to be 20-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranosyl-20(S)-protopanaxadiol on the basis of spectral analysis. Its
Tian Wang et al.
European journal of pharmacology, 636(1-3), 121-125 (2010-04-08)
The present study was designed to evaluate the effect of ginsenoside Rb3 on myocardial injury and heart function impairment induced by isoproterenol in rats. To induce myocardial ischemia, Sprague-Dawley rats were subcutaneously injected with isoproterenol (20mg/kg). Cardiac marker enzymes and
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