42754
Ginsenoside Rk1
analytical standard
别名:
(3β, 12β)-12-Hydroxydammara-20,24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
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关于此项目
经验公式（希尔记法）:
C42H70O12
化学文摘社编号:
分子量:
767.00
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24
grade
analytical standard
Quality Level
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
format
neat
storage temp.
2-8°C
SMILES string
CC1(C)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]4(C)[C@@]1([H])CC[C@]5(C)[C@]4([H])C[C@@H](O)[C@@]6([H])[C@@]5(C)CC[C@@]6(C(CCC=C(C)C)=C)[H]
InChI
1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10,23-38,43-50H,3,9,11-20H2,1-2,4-8H3/t23-,24-,25-,26-,27+,28-,29+,30
InChI key
KWDWBAISZWOAHD-MHOSXIPRSA-N
General description
Ginsenoside Rk1 is the major bioactive component isolated from heat-processed Panax ginseng Meyer (ginseng) plants. It is a monomeric compound that has been reported to exhibit anti-inflammatory, anti-allergic, and anti-tumor properties and is utilized for the treatment of cancer and diabetes mellitus.
Application
Ginsenoside Rk1 may be used as an analytical reference standard for the determination of the analyte in Panax ginseng preparations and Chinese medicine formula Sheng-Mai San (SMS) and rat plasma samples (post administration of SMS) by chromatography techniques.
Other Notes
This compound is commonly found in plants of the genus: panax
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis
Kim YJ, et al.
Biological & Pharmaceutical Bulletin, 31(5), 826-830 (2008)
Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography
Park HW, et al.
Journal of ginseng research, 37(4), 457-457 (2013)
Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264. 7 cells by inhibiting the Jak2/Stat3 pathway
Qian YU, et al.
Chinese Journal of Natural Medicines, 15(10), 751-757 (2017)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 42754-5MG | 04061832104607 |