43073
扑热息痛β-D-葡萄糖醛酸苷
analytical standard
别名:
p-Acetamidophenyl β-D-glucuronide, Acetaminophen glucuronide
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关于此项目
经验公式（希尔记法）:
C14H17NO8
化学文摘社编号:
分子量:
327.29
Beilstein:
46644
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥98.5% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤12.0% water
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
O[C@@H]1[C@@H](O)[C@H](OC2=CC=C(NC(C)=O)C=C2)O[C@H](C(O)=O)[C@H]1O
InChI
1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1
InChI key
IPROLSVTVHAQLE-BYNIDDHOSA-N
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sifeng Mao et al.
Lab on a chip, 12(1), 219-226 (2011-11-19)
In this work, we developed a microfluidic device for the imitation of drug metabolism in human liver and its cytotoxicity on cells. The integrated microfluidic device consists of three sections: (1) bioreactors containing poly(ethylene) glycol (PEG) hydrogel encapsulated human liver
Nicole J Barshop et al.
Journal of pediatric gastroenterology and nutrition, 52(2), 198-202 (2011-01-18)
: The aim of the study was to evaluate UDP-glucuronyltransferase activity and the pharmacokinetics of a single oral dose of acetaminophen (APAP) in children with nonalcoholic fatty liver disease (NAFLD). : Twelve boys 10 to 17 years old with biopsy-proven
Carolina I Ghanem et al.
Biochemical pharmacology, 77(10), 1621-1628 (2009-05-12)
Development of resistance to toxic effects of acetaminophen (APAP) was reported in rodents and humans, though the mechanism is only partially understood. We examined in rats the effect of administration with subtoxic daily doses (0.2, 0.3, and 0.6g/kg, i.p.) of
Cristina Barosa et al.
Magnetic resonance in medicine, 70(2), 315-319 (2012-10-02)
Plasma glucose (2) H-enrichment in positions 5 ((2) H5) and 2 ((2) H2) from deuterated water ((2) H2 O) provides a measure of the gluconeogenic contribution to endogenous glucose production. Urinary glucuronide analysis can circumvent blood sampling but it is
María L Ruiz et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(11), 2060-2066 (2007-08-10)
The effect of spironolactone (SL) administration on 17alpha-ethynylestradiol (EE)-induced cholestasis was studied, with emphasis on expression and activity of Mrps. Adult male Wistar rats were divided into the following groups: EE (5 mg/kg daily for 5 days, s.c.), SL (200
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