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43530

LC-MS 利血平标准溶液

Name: LC-MS 利血平标准溶液
Brand: SIAL

analytical standard, for LC-MS

别名:

利血平, (3β, 16β, 17α, 18β, 20α)-11,17-二甲氧基-18-[(3,4,5-三甲氧基苯甲酰基)氧基]育亨烷-16-羧酸甲酯

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关于此项目

经验公式（希尔记法）:

C₃₃H₄₀N₂O₉

化学文摘社编号:

50-55-5

分子量:

608.68

UNSPSC Code:

41121800

NACRES:

NB.21

PubChem Substance ID:

329756346

MDL number:

MFCD00005091

Beilstein/REAXYS Number:

102014

Quality level:

100

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属性

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

concentration

5 mg/L in water: isopropyl alcohol (1:1)

technique(s)

LC/MS: suitable

mp

~265 °C (dec.)

suitability

corresponds for mass spectrometry

storage temp.

2-8°C

SMILES string

CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6

InChI

1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1

InChI key

QEVHRUUCFGRFIF-MDEJGZGSSA-N

说明

General description

Reserpine is a 36 carbon indole alkaloid mostly used as a tranquilizing agent in medicine. It is mostly used as drug for hypertension.

Application

It was used as mass recalibration standard in coupling capillary electrophoresis with electrospray ionization time-of-flight mass spectrometry (CE-TOFMS) to overcome the problem of decreasing the sensitivity during the detection of metabolome differential display.

Biochem/physiol Actions

抑制儿茶酚胺和血清素的囊泡摄取。

pictograms

GHS02,GHS07

signalword

Danger

hcodes

H225,H319,H336

pcodes

P210 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

71.6 °F - closed cup

flash_point_c

22.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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Stimulation of reserpine biosynthesis in the callus of Rauvolfia tetraphylla L. by precursor feeding.

Anitha, S and BD Ranjitha Kumari

African Journal of Biotechnology, 5.8, 659-659 (2006)

Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption.

Tomoyoshi Soga et al.

The Journal of biological chemistry, 281(24), 16768-16776 (2006-04-13)

Metabolomics is an emerging tool that can be used to gain insights into cellular and physiological responses. Here we present a metabolome differential display method based on capillary electrophoresis time-of-flight mass spectrometry to profile liver metabolites following acetaminophen-induced hepatotoxicity. We

Deep brain stimulation of the substantia nigra pars reticulata improves forelimb akinesia in the hemiparkinsonian rat.

Alexander C Sutton et al.

Journal of neurophysiology, 109(2), 363-374 (2012-10-19)

Deep brain stimulation (DBS) employing high-frequency stimulation (HFS) is commonly used in the globus pallidus interna (GPi) and the subthalamic nucleus (STN) for treating motor symptoms of patients with Parkinson's disease (PD). Although DBS improves motor function in most PD

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货号	GTIN
43530-4.5ML-F	04061832113531