十二烷基硫酸钠

Name: 十二烷基硫酸钠
Brand: SIAL

ACS reagent, ≥99.0%

别名:

SDS, 十二烷基硫酸盐钠盐, 十二烷基硫酸钠, 月桂基硫酸盐钠盐, 月桂基硫酸钠

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线性分子式:

CH₃(CH₂)₁₁OSO₃Na

化学文摘社编号:

151-21-3

分子量:

288.38

NACRES:

NA.21

PubChem Substance ID:

24867284

eCl@ss:

39093306

UNSPSC Code:

12161900

EC Number:

205-788-1

MDL number:

MFCD00036175

Beilstein/REAXYS Number:

3599286

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产品名称

十二烷基硫酸钠, ACS reagent, ≥99.0%

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

grade

ACS reagent

description

anionic
62

assay

≥99.0%

form

solid

mol wt

288.38 g/mol

Quality Level

200

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤0.06 meq/g Titr. Base
≥96.0% fatty alcohols
<4.0% unsulfated alcohols

loss

≤1.0% loss on drying

mp

204-207 °C (lit.)

solubility

H₂O: soluble 1 gm in 10 ml (opalescent solution)

density

1.03 g/cm³ at 20 °C

cation traces

heavy metals (as Pb): ≤0.002%

λ

3 %H₂O reference

UV absorption

λ: 220-350 nm A_max: ≤0.1

HLB

greener alternative category

Aligned

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Application

十二烷基硫酸钠被用作一种检测化合物，用于研究解淀粉芽孢杆菌KPS46是否能在大豆（Glycine max L.）中诱导针对几种疾病的引发、信号传导、蛋白质产生以及系统保护。

阴离子洗涤剂

Biochem/physiol Actions

十二烷基硫酸钠（SDS）是一种阴离子去污剂，可通过疏水相互作用与蛋白质形成复合物。已有研究报道称蛋白质-SDS复合物的流体动力学功能受其多肽链长度的控制。因此，基于SDS的电泳技术可根据蛋白质的分子量而将蛋白质分子进行分离。此外，SDS还可溶解细胞膜并提取膜结合蛋白。

Features and Benefits

多功能表面活性剂，适合分子生物学和生物化学研究
经检测确证重金属污染少，适合多种用途

General description

十二烷基硫酸钠(SDS)也称月桂基硫酸钠，是多功能的阴离子表面活性剂，广泛用于细胞生物学、生物化学和各种工业领域。疏水性的烃链尾端和亲水性的硫酸盐头基构成了它的两亲性，作为去垢剂可有效地溶解和变性蛋白质、脂质和其他疏水分子。

蛋白质生物化学中，SDS在蛋白质提取和SDS-PAGE（十二烷基硫酸钠-聚丙烯酰胺凝胶电泳）中起关键作用。SDS通过破坏蛋白质的二、三级结构使其变性，使所有蛋白质能以相同的线性结构在聚丙烯酰胺凝胶电泳中移动，得以按分子量大小分离。SDS-PAGE这项技术已经成为分析蛋白质大小和纯度不可或缺的工具。

除了蛋白质分析，SDS还可用于核酸提取和杂交技术。去垢剂特性可裂解细胞、溶解细胞组分，便于提取DNA和RNA。因此SDS也是各种分子生物学实验的重要工具，包括PCR（聚合酶链式反应）和Southern blotting。作为功能多样的表面活性剂，十二烷基硫酸钠可溶解、变性和分离生物分子，广泛用于细胞生物学和生化研究。

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Other Notes

如需了解生化试剂系列的更多信息，请填写此表。

pictograms

GHS02,GHS05,GHS07

signalword

Danger

hcodes

H228,H302 + H332,H315,H318,H335,H412

pcodes

P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Priming, signaling, and protein production associated with induced resistance by Bacillus amyloliquefaciens KPS46.

Natthiya Buensanteai

World Journal of Microbiology & Biotechnology, 25 (2009)

Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes.

K Fujimoto

Journal of cell science, 108 ( Pt 11), 3443-3449 (1995-11-01)

We propose a new electron microscopic method, the sodium dodecylsulphate (SDS)-digested freeze-fracture replica labeling technique, to study the two-dimensional distribution of integral membrane proteins in cellular membranes. Unfixed tissue slices were frozen with liquid helium, freeze-fractured, and replicated in a

The gross conformation of protein-sodium dodecyl sulfate complexes.

J A Reynolds et al.

The Journal of biological chemistry, 245(19), 5161-5165 (1970-10-10)

Bacterial effector modulation of host E3 ligase activity suppresses PAMP-triggered immunity in rice.

Kazuya Ishikawa et al.

Nature communications, 5, 5430-5430 (2014-11-13)

Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in

A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer.

Shane Stegeman et al.

Endocrine-related cancer, 22(2), 265-276 (2015-02-12)

The oncogene MDM4, also known as MDMX or HDMX, contributes to cancer susceptibility and progression through its capacity to negatively regulate a range of genes with tumour-suppressive functions. As part of a recent genome-wide association study it was determined that

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Surfactant-assisted dispersion of single-walled carbon nanotubes for debundling or exfoliation in dispersion procedures.

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十二烷基硫酸钠

ACS reagent, ≥99.0%

选择尺寸

关于此项目

主要文件

属性

产品名称

InChI key

InChI

SMILES string

grade

description

assay

form

mol wt

Quality Level

greener alternative product characteristics

sustainability

impurities

loss

mp

solubility

density

cation traces

λ

UV absorption

HLB

greener alternative category

相关类别

说明

Application

Biochem/physiol Actions

Features and Benefits

General description

Other Notes

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

target_organs

存储类别

wgk

flash_point_f

flash_point_c

ppe

文件

分析证书(COA)

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