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Merck
CN

43760

Sigma-Aldrich

5,5′-二硫代双(2-硝基苯甲酸)

≥97.5% (HPLC)

别名:

6,6′-二硝基-3,3′-二硫代苯甲酸, DTNB, Ellman 试剂, 二硫代硝基苯甲酸, 双(3-羧基-4-硝基苯基)二硫

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关于此项目

线性分子式:
[-SC6H3(NO2)CO2H]2
化学文摘社编号:
分子量:
396.35
Beilstein:
1896821
EC 号:
MDL编号:
UNSPSC代码:
12352200
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方案

≥97.5% (HPLC)

mp

240-245 °C (dec.) (lit.)
~240 °C (dec.)

SMILES字符串

OC(=O)c1cc(SSc2ccc(c(c2)C(O)=O)[N+]([O-])=O)ccc1[N+]([O-])=O

InChI

1S/C14H8N2O8S2/c17-13(18)9-5-7(1-3-11(9)15(21)22)25-26-8-2-4-12(16(23)24)10(6-8)14(19)20/h1-6H,(H,17,18)(H,19,20)

InChI key

KIUMMUBSPKGMOY-UHFFFAOYSA-N

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其他说明

For the modification and quantitative detection of sulfhydryl groups; Re-examination of molar absorption coefficient; Derivatization of thiols for HPLC.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K. Kuwata et al.
Analytical Chemistry, 54, 1082-1082 (1982)
Ellman's reagent: 5,5'-dithiobis(2-nitrobenzoic acid)--a reexamination.
P W Riddles et al.
Analytical biochemistry, 94(1), 75-81 (1979-04-01)
Tissue sulfhydryl groups.
G L ELLMAN
Archives of biochemistry and biophysics, 82(1), 70-77 (1959-05-01)
Malgorzata Boczkowska et al.
Structure (London, England : 1993), 16(5), 695-704 (2008-05-09)
Previous structures of Arp2/3 complex, determined in the absence of a nucleation-promoting factor and actin, reveal its inactive conformation. The study of the activated structure has been hampered by uncontrollable polymerization. We have engineered a stable activated complex consisting of
Anne Bertling et al.
Arteriosclerosis, thrombosis, and vascular biology, 32(8), 1979-1990 (2012-04-28)
Staphylococcus aureus can induce platelet aggregation. The rapidity and degree of this correlates with the severity of disseminated intravascular coagulation, and depends on platelet peptidoglycans. Surface-located thiol isomerases play an important role in platelet activation. The staphylococcal extracellular adherence protein

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