44925
DL-同型半胱氨酸
analytical standard
别名:
2-氨基-4-巯基丁酸
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关于此项目
线性分子式:
HSCH2CH2CH(NH2)COOH
化学文摘社编号:
分子量:
135.18
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-222-9
Beilstein/REAXYS Number:
1721683
MDL number:
InChI key
FFFHZYDWPBMWHY-UHFFFAOYSA-N
InChI
1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)
SMILES string
NC(CCS)C(O)=O
grade
analytical standard
assay
≥95% (T)
optical activity
[α]/D 0±1°, c = 1 in H2O
shelf life
limited shelf life, expiry date on the label
analyte chemical class(es)
amino acids, peptides, proteins
technique(s)
HPLC: suitable
color
white to off-white
mp
232-233 °C (lit.)
application(s)
food and beverages
format
neat
storage temp.
−20°C
Quality Level
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Application
同型半胱氨酸可用作分析参考标准品，通过不同色谱技术，定量生物样品中的同型半胱胺酸 。
有关合适仪器技术的更多信息，请参考产品的分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
血浆同型半胱氨酸水平升高是冠心病和癌变的危险因素；可能是肿瘤细胞生长的标志物。
Analysis Note
鉴别 (LS-MS)：鉴别符合规定
Disclaimer
氩气下储存
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ghulam Mohammad et al.
International journal of molecular sciences, 21(5) (2020-03-11)
High homocysteine is routinely observed in diabetic patients, and this non-protein amino acid is considered as an independent risk factor for diabetic retinopathy. Homocysteine biosynthesis from methionine forms S-adenosyl methionine (SAM), which is a major methyl donor critical in DNA
Rapid measurement of total plasma homocysteine by HPLC
Frick B, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 331(1-2), 19-23 (2003)
Joshua A Dubland et al.
Journal of mass spectrometry and advances in the clinical lab, 20, 1-10 (2021-11-26)
Inborn errors of propionate, cobalamin and methionine metabolism are targets for Newborn Screening (NBS) in most programs world-wide, and are primarily screened by analyzing for propionyl carnitine (C3) and methionine in dried blood spot (DBS) cards using tandem mass spectrometry
Pre-column derivatization high-performance liquid chromatographic method for determination of cysteine, cysteinyl-glycine, homocysteine and glutathione in plasma and cell extracts
Katrusiak.EA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 758(2), 207-212 (2001)
James Ampadu et al.
International journal of cardiology, 178, 12-23 (2014-12-03)
It has been estimated that 5.1million Americans suffer from heart failure. Cognitive impairment has been described as a consequence of heart failure in numerous studies spanning the last three decades. This systematic review helps differentiate "cognitive impairment" into mild cognitive
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