44925
DL-同型半胱氨酸
analytical standard
别名:
2-氨基-4-巯基丁酸
等级
analytical standard
质量水平
方案
≥95% (T)
旋光性
[α]/D 0±1°, c = 1 in H2O
保质期
limited shelf life, expiry date on the label
分析物化学类别
amino acids, peptides, proteins
技术
HPLC: suitable
颜色
white to off-white
mp
232-233 °C (lit.)
应用
food and beverages
包装形式
neat
储存温度
−20°C
SMILES字符串
NC(CCS)C(O)=O
InChI
1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)
InChI key
FFFHZYDWPBMWHY-UHFFFAOYSA-N
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应用
同型半胱氨酸可用作分析参考标准品,通过不同色谱技术,定量生物样品中的同型半胱胺酸 。
有关合适仪器技术的更多信息,请参考产品的分析证书。如需进一步支持,请联系技术服务。
生化/生理作用
血浆同型半胱氨酸水平升高是冠心病和癌变的危险因素;可能是肿瘤细胞生长的标志物。
分析说明
鉴别 (LS-MS):鉴别符合规定
免责声明
氩气下储存
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Rapid measurement of total plasma homocysteine by HPLC
Frick B, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 331(1-2), 19-23 (2003)
Ghulam Mohammad et al.
International journal of molecular sciences, 21(5) (2020-03-11)
High homocysteine is routinely observed in diabetic patients, and this non-protein amino acid is considered as an independent risk factor for diabetic retinopathy. Homocysteine biosynthesis from methionine forms S-adenosyl methionine (SAM), which is a major methyl donor critical in DNA
Joshua A Dubland et al.
Journal of mass spectrometry and advances in the clinical lab, 20, 1-10 (2021-11-26)
Inborn errors of propionate, cobalamin and methionine metabolism are targets for Newborn Screening (NBS) in most programs world-wide, and are primarily screened by analyzing for propionyl carnitine (C3) and methionine in dried blood spot (DBS) cards using tandem mass spectrometry
Pre-column derivatization high-performance liquid chromatographic method for determination of cysteine, cysteinyl-glycine, homocysteine and glutathione in plasma and cell extracts
Katrusiak.EA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 758(2), 207-212 (2001)
Yifan Huang et al.
International journal of molecular sciences, 15(4), 6298-6313 (2014-04-17)
Maternal nutrition may influence metabolic profiles in offspring. We aimed to investigate the effect of maternal folic acid supplement on glucose metabolism in mouse offspring fed a high-fat diet (HFD). Sixty C57BL/6 female mice were randomly assigned into three dietary
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