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Merck
CN

45379

十氯酮

PESTANAL®, analytical standard

别名:

Kepone, 开蓬, 十氯酮

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关于此项目

经验公式（希尔记法）:
C10Cl10O
化学文摘社编号:
143-50-0
分子量:
490.64
NACRES:
NA.24
PubChem Substance ID:
329756686
UNSPSC Code:
41116107
EC Number:
205-601-3
MDL number:
MFCD00213544

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InChI key

LHHGDZSESBACKH-UHFFFAOYSA-N

InChI

1S/C10Cl10O/c11-2-1(21)3(12)6(15)4(2,13)8(17)5(2,14)7(3,16)9(6,18)10(8,19)20

SMILES string

ClC1(Cl)C2(Cl)C3(Cl)C4(Cl)C(=O)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

100

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General description

Chlordecone is a chlorinated cyclodiene pesticide and a persistent environmental contaminant, obtained via degradation of mirex.

Application

Chlordecone may be used as an analytical reference standard for the quantification of the analyte in animals using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL8655
BCCB4861

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Development and validation of an HPLC-MS/MS method with QuEChERS extraction using isotopic dilution to simultaneously analyze chlordecone and chlordecol in animal livers
Saint-Hilaire M, et al.
Food Chemistry, 252, 147-153 (2018)
Toxicological Study of Pesticides in Animals (1990)
High-performance liquid chromatography separation of chlordecone and its metabolites
Chromatographia, 22(1-6), 165-167 (1986)
Fei Wang et al.
International immunopharmacology, 7(13), 1808-1812 (2007-11-13)
In murine models of systemic lupus erythematosus (SLE), administration of either prolactin or estradiol (E2) increases autoimmunity, and there is evidence that elevated prolactin in response to E2 administration may contribute substantially to E2 effects. Hormonal influence on SLE can
José-Manuel Zaldívar et al.
Chemosphere, 82(11), 1547-1555 (2010-12-21)
There is the need to integrate existing toxicity data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This integration would also reduce time and cost-consuming aspects of these tests and reduce animal
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