45706
华法林
PESTANAL®, analytical standard
别名:
4-羟基-3-(3-氧代-1-苯基丁基)-2H-1-苯并吡喃-2-酮, 杀鼠灵钠
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关于此项目
经验公式（希尔记法）:
C19H16O4
化学文摘社编号:
分子量:
308.33
Beilstein:
8868198
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
产品线
PESTANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
162-164 °C (lit.)
应用
agriculture
environmental
包装形式
neat
SMILES字符串
CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
InChI
1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
InChI key
PJVWKTKQMONHTI-UHFFFAOYSA-N
基因信息
human ... VKORC1(79001)
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应用
华法林是一种常用于预防血栓形成和血栓栓塞的抗凝剂。 其已在许多中风和肺纤维化患者研究中使用。 它已用于研究潜在风险以及与其他药物和食物的相互作用。
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
生化/生理作用
华法林由两种活性对映体R和S形式的外消旋混合物组成。 华法林比普通抗凝肝素作用慢。 华法令可抑制钙依赖性凝血因子II、VII、IX和X的生物活性形式的维生素K依赖性合成。它可抑制调节因子蛋白C、蛋白S和蛋白Z。
法律信息
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
仅限于专业用户。注意 — 避免接触 — 使用前请阅读说明书。
警示用语：
Danger
危险分类
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1 Oral
靶器官
Blood
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
法规信息
危险化学品
农药列管产品
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实验方案
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Chromatograms
application for HPLC
application for HPLC
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