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Merck
CN

46036

溴鼠隆

PESTANAL®, analytical standard

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关于此项目

经验公式（希尔记法）:
C31H23BrO3
化学文摘社编号:
56073-10-0
分子量:
523.42
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757068
EC Number:
259-980-5
Beilstein/REAXYS Number:
8171403
MDL number:
MFCD00084803

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产品名称

溴鼠隆, PESTANAL®, analytical standard

InChI key

VEUZZDOCACZPRY-UHFFFAOYSA-N

InChI

1S/C31H23BrO3/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,33H,17-18H2

SMILES string

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccc(Br)cc5)C(=O)Oc6ccccc16

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Quality Level

100

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相关类别

Application

Brodifacoum may be used as an analytical reference standard for the quantification of the analyte in animal samples and biological samples using different chromatography techniques..
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Brodifacoum is an anticoagulant rodenticide, widely used for the control of rodent population via inhibition of the vitamin K epoxide reductase, causing blood clotting alterations, leading to haemorrhaging as the ultimate cause of death.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - STOT RE 1

target_organs

Blood

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN2802
BCCF1546
BCBS3140V
BCBR9161V

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. For what applications can Product 46036, Brodifacoum, be used?

    This product consists of a coumarin analog. It has anticoagulant activity and has been described as a rodenticide.

  6. What is the purity of Product 46036, Brodifacoum?

    This product does not have a purity specification. However, the purity is provided on the certificate of analysis of each lot.

  7. What is Product 46036, Brodifacoum, soluble in?

    This product is insoluble in water. It is slightly soluble in alcohol and benzene. It is soluble in acetone and chloroform.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

The determination of the anticoagulant rodenticide brodifacoum in blood serum by liquid chromatography with fluorescence detection
Felice.JL and Murphy.JM
Journal of Analytical Toxicology, 13(4), 229-231 (1989)
Reversed-phase HPLC determination of eight anticoagulant rodenticides in animal liver
Fauconnet.V, et al.
Journal of Analytical Toxicology, 21(7), 548-553 (1997)
Naren Gunja et al.
Clinical toxicology (Philadelphia, Pa.), 49(5), 385-390 (2011-07-12)
Brodifacoum is a widely available superwarfarin used as a commercial rodenticide. Toxicity from long-acting anticoagulant rodenticides, primarily from uncontrolled bleeding, has been reported. Very little published toxicokinetic data are available for human brodifacoum poisoning. Management is also contentious with uncertainty
Alan P Buckle et al.
Pest management science, 68(12), 1579-1585 (2012-09-26)
The tyrosine to cysteine amino acid substitution at location 139 of the vkorc1 protein (i.e. tyrosine139cysteine or Y139C) is the most widespread anticoagulant resistance mutation in Norway rats (Rattus norvegicus Berk.) in Europe. Field trials were conducted to determine the
Servet Altay et al.
Cardiovascular journal of Africa, 23(9), e9-e11 (2012-10-31)
Superwarfarins (brodifacoum, difenacoum, bromodialone and chlorphacinone) are anticoagulant rodenticides that were developed in 1970s to overcome resistance to warfarin in rats. A 26-year-old previously healthy man was admitted to the emergency department with epigastric pain, severe upper and lower gastrointestinal
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