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Merck
CN

46161

地美环素 盐酸盐 水合物

VETRANAL®, analytical standard

别名:

去甲基金霉素 盐酸盐

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关于此项目

经验公式（希尔记法）:
C21H21ClN2O8 · HCl · xH2O
化学文摘社编号:
64-73-3
分子量:
501.31 (anhydrous basis)
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757091
EC Number:
200-592-2
Beilstein/REAXYS Number:
5705221
MDL number:
MFCD00149217

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产品名称

地美环素 盐酸盐 水合物, VETRANAL®, analytical standard

InChI key

LZJOUJFCRCXBBC-XZJYMHMKSA-N

InChI

1S/C21H21ClN2O8.ClH.H2O/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H;1H2/t6-,7-,14-,15-,21-;;/m0../s1

SMILES string

O.Cl.CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

200

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相关类别

Application

Demeclocycline hydrochloride hydrate may be used as an internal standard for the determination of:
  • Oxytetracycline and tetracycline in pig manure samples by ultra-high performance liquid chromatography (UHPLC) coupled to triple quadrupole mass spectrometer equipped with electrospray ionization source (QqQ-ESI-MS/MS) and dynamic multiple reaction monitoring (dMRM) mode of detection.
  • Oxytetracycline hydrochloride in dairy products by UHPLC-QqQ-ESI-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: tetracycline

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL9389
BCCC8240
BCBX9925

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the solubility of Product 46161, Demeclocycline hydrochloride hydrate? 

    Product 46161, Demeclocycline hydrochloride hydrate, is soluble in water, with heat as needed.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

J Bousek et al.
Journal of environmental management, 223, 545-553 (2018-07-01)
The fate of four widely used veterinary antibiotics (doxycycline, flumequine, oxytetracycline and tetracycline) during manure upcycling was investigated at laboratory and pilot scale. The pilot was operated continuously, while the laboratory scale in batch mode. Both set-ups consisted of anaerobic
Development and Validation of a Multi-class UHPLC-MS/MS Method for Determination of Antibiotic Residues in Dairy Products
Schwaiger B, et al.
Food Analytical Methods, 14, 1417-1434 (2018)
P Lenherr et al.
International endodontic journal, 45(10), 942-949 (2012-04-18)
To investigate the discoloration potential of endodontic materials using a bovine tooth model. Two hundred and 10 dentine-enamel cuboid blocks (10 × 10 × 3.5 mm) were prepared out of the middle thirds of bovine tooth crowns. Standardized cavities were
B Athanassiadis et al.
Australian dental journal, 55(2), 150-155 (2010-07-08)
The in vitro antimicrobial activity of a series of endodontic medicaments and their bases against biofilms of Enterococcus faecalis was investigated. The medicaments tested were Pulpdent paste, Ledermix paste, a 50:50 Ledermix and Pulpdent mixture, and a replica of Ledermix
B Athanassiadis et al.
Australian dental journal, 55(3), 298-305 (2010-10-05)
The aim of this study was to investigate the antimicrobial effect of endodontic medicaments and their bases in the presence of dentine powder. The medicaments tested were Ledermix paste, Pulpdent paste, a 50:50 combination of the Pulpdent:Ledermix and their bases.
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