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Merck
CN

46182

双氯青霉素 钠盐 水合物

VETRANAL®, analytical standard

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关于此项目

经验公式(希尔记法):
C19H16Cl2N3NaO5S · xH2O
化学文摘社编号:
分子量:
492.31 (anhydrous basis)
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
206-444-3
Beilstein/REAXYS Number:
4778711
MDL number:
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InChI key

SIGZQNJITOWQEF-VICXVTCVSA-M

InChI

1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

SMILES string

[Na+].[H]O[H].Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)-c4c(Cl)cccc4Cl

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

General description

Chemical structure: β-lactam
Dicloxacillins are mostly used β-lactam class of antibiotics that have major applications in veterinary medicines.

Application

Dicloxacillin sodium salt hydrate may be used as a reference standard for the determination of dicloxacillin sodium salt hydrate in:
  • Animal feed by pressurised liquid extraction (PLE) with liquid chromatography-quadrupole-linear ion-trap mass spectrometry (LC-QLIT-MS/MS) operating on multiple reaction monitoring mode (MRM).
  • Gilthead sea bream (Sparus aurata) by ultra-high pressure liquid chromatography (UHPLC) in conjunction with MS/MS.
  • Foodstuffs of animal origin and in milk by UHPLC-MS/MS equipped with electrospray ionisation (ESI).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Multiclass analysis of 23 veterinary drugs in milk by ultraperformance liquid chromatography-electrospray tandem mass spectrometry
Tang YY, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 881, 12-19 (2012)
Multiresidue determination of veterinary drugs in aquaculture fish samples by ultra high performance liquid chromatography coupled to tandem mass spectrometry
Lopes RP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 895(3), 39-47 (2012)
Development and validation of a pressurised liquid extraction liquid chromatography-electrospray-tandem mass spectrometry method for ?-lactams and sulfonamides in animal feed
Kantiani LF, et al.
Journal of Chromatography A, 1217(26), 4247-4254 (2010)
High-throughput multiclass method for antibiotic residue analysis by liquid chromatography-tandem mass spectrometry
Chico J, et al.
Journal of Chromatography A, 1213(2), 189-199 (2008)
Determination of antibacterials in animal feed by pressurized liquid extraction followed by online purification and liquid chromatography-electrospray tandem mass spectrometry
Kantiani L, et al.
Analytical and Bioanalytical Chemistry, 398(3), 1195-1205 (2010)

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