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经验公式(希尔记法):
C19H16Cl2N3NaO5S · xH2O
化学文摘社编号:
分子量:
492.31 (anhydrous basis)
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
206-444-3
Beilstein/REAXYS Number:
4778711
MDL number:
InChI key
SIGZQNJITOWQEF-VICXVTCVSA-M
InChI
1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1
SMILES string
[Na+].[H]O[H].Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)-c4c(Cl)cccc4Cl
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Quality Level
General description
Chemical structure: β-lactam
Dicloxacillins are mostly used β-lactam class of antibiotics that have major applications in veterinary medicines.
Application
Dicloxacillin sodium salt hydrate may be used as a reference standard for the determination of dicloxacillin sodium salt hydrate in:
- Animal feed by pressurised liquid extraction (PLE) with liquid chromatography-quadrupole-linear ion-trap mass spectrometry (LC-QLIT-MS/MS) operating on multiple reaction monitoring mode (MRM).
- Gilthead sea bream (Sparus aurata) by ultra-high pressure liquid chromatography (UHPLC) in conjunction with MS/MS.
- Foodstuffs of animal origin and in milk by UHPLC-MS/MS equipped with electrospray ionisation (ESI).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
Multiclass analysis of 23 veterinary drugs in milk by ultraperformance liquid chromatography-electrospray tandem mass spectrometry
Tang YY, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 881, 12-19 (2012)
Multiresidue determination of veterinary drugs in aquaculture fish samples by ultra high performance liquid chromatography coupled to tandem mass spectrometry
Lopes RP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 895(3), 39-47 (2012)
Development and validation of a pressurised liquid extraction liquid chromatography-electrospray-tandem mass spectrometry method for ?-lactams and sulfonamides in animal feed
Kantiani LF, et al.
Journal of Chromatography A, 1217(26), 4247-4254 (2010)
High-throughput multiclass method for antibiotic residue analysis by liquid chromatography-tandem mass spectrometry
Chico J, et al.
Journal of Chromatography A, 1213(2), 189-199 (2008)
Determination of antibacterials in animal feed by pressurized liquid extraction followed by online purification and liquid chromatography-electrospray tandem mass spectrometry
Kantiani L, et al.
Analytical and Bioanalytical Chemistry, 398(3), 1195-1205 (2010)
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