46232
安乃近 一水合物
VETRANAL®, analytical standard
别名:
二吡喃酮, 诺瓦经
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关于此项目
经验公式（希尔记法）:
C13H16N3NaO4S · H2O
化学文摘社编号:
分子量:
351.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3865381
产品名称
安乃近 一水合物, VETRANAL®, analytical standard
InChI key
UNZIDPIPYUMVPA-UHFFFAOYSA-M
InChI
1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1
SMILES string
O.[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)c2ccccc2
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
Gene Information
human ... PTGS1(5742), PTGS2(5743)
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Application
Metamizol may be used as a reference standard for the determination of metamizol in pharmaceutical formulations by reversed-phase high-performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Metamizol is an active pharmaceutical ingredient with both analgesic and antipyretic effects, primarily used to relieve pain caused by neuritis and neuralgia.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
涉药品监管产品
此项目有
Simultaneous Determination Of Metamizole, Thiamin And Pyridoxin In Multicomponent Tablet by RP-HPLC.
Chotimah C.
Journal of Food and Pharmaceutical Sciences, 2(3) (2014)
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Tina Kirchner et al.
Mediators of inflammation, 2012, 849136-849136 (2012-04-07)
The formation of neutrophil extracellular traps (NETs) depends on the generation of reactive oxygen species (ROS). Previous studies revealed that both NADPH oxidase and myeloperoxidase (MPO) are required for NET release. However, the contribution of various ROS as well as
Sylwia Magiera et al.
Journal of AOAC International, 97(6), 1526-1537 (2015-01-30)
A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs were extracted from urine samples and then separated on a Zorbax Rapid Resolution
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