46256
红霉素 A 二水合物
VETRANAL®, analytical standard
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关于此项目
经验公式（希尔记法）:
C37H67NO13 · xH2O
化学文摘社编号:
分子量:
733.93 (anhydrous basis)
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
204-040-1
NACRES:
NA.24
grade
analytical standard
Quality Segment
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
gas chromatography (GC): suitable, HPLC: suitable
application(s)
clinical testing
format
neat
SMILES string
N([C@@H]1[C@H]([C@@H](O[C@@H](C1)C)O[C@@H]2[C@H]([C@@H]([C@H](C(=O)O[C@@H]([C@]([C@@H]([C@H](C(=O)C(C[C@]2(O)C)C)C)O)(O)C)CC)C)O[C@@H]3O[C@H]([C@@H]([C@@](C3)(OC)C)O)C)C)O)(C)C.O.O
InChI
1S/C37H67NO13.2H2O/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;;/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2*1H2/t18?,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;;/m1../s1
InChI key
IWGQNYZQLVGGCS-ZKSNWDMWSA-N
Application
Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site.
Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.
Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.
Preparation Note
This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)