46429
甲巯咪唑
VETRANAL®, analytical standard
别名:
1-甲基-2-咪唑硫醇, 2-巯基-1-甲基咪唑
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关于此项目
经验公式（希尔记法）:
C4H6N2S
化学文摘社编号:
分子量:
114.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-482-4
Beilstein/REAXYS Number:
108646
MDL number:
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
144-147 °C (lit.)
application(s)
cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
format
neat
SMILES string
CN1C=CNC1=S
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Information
human ... TPO(7173)
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General description
甲硫咪唑是一种甲状腺激素抑制剂和一种抗激素药，广泛用于甲亢治疗药物。
Application
甲巯咪唑可作为混合模式固相萃取-反相高效液相色谱-紫外检测法（MMSPE-RP-HPLC-UV）测定鱼匀浆中分析物的参考标准品。
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
target_organs
Endocrine system
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1A - Skin Sens. 1 - STOT RE 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Stijn L J Van Herck et al.
The Journal of endocrinology, 218(1), 105-115 (2013-04-24)
Methimazole (MMI) is an anti-thyroid drug used in the treatment of chronic hyperthyroidism. There is, however, some debate about its use during pregnancy as MMI is known to cross the mammalian placenta and reach the developing foetus. A similar problem
Mal-Soon Shin et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(3), 214-223 (2013-01-19)
Thyroid hormones play a crucial role in new neuron production and maturation during brain development. Physical exercise is known to promote cell survival and functional recovery after brain injuries. In the present study, we investigated the effects of treadmill exercise
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
Sangmi Ock et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(12), 4899-4908 (2013-08-29)
Although thyroid-stimulating hormone (TSH) is known to be a major regulator of thyroid hormone biosynthesis and thyroid growth, insulin-like growth factor 1 (IGF-1) is required for mediating thyrocyte growth in concert with TSH in vitro. We generated mice with thyrocyte-selective
M Clementi et al.
American journal of medical genetics, 83(1), 43-46 (1999-03-17)
We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy (from first to seventh gestational week), and define a specific malformation pattern related to prenatal methimazole exposure and consisting
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 46429-250MG | 04061834089452 |
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