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Merck
CN

46502

Supelco

呋喃妥因

VETRANAL®, analytical standard

别名:

N -（5-硝基-2-呋喃亚基）-1-氨基乙内酰脲, 呋喃坦啶, 硝基呋喃妥因

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关于此项目

经验公式（希尔记法）:
C8H6N4O5
化学文摘社编号:
67-20-9
分子量:
238.16
Beilstein:
893207
EC 号:
200-646-5
MDL编号:
MFCD00003224
UNSPSC代码:
41116107
PubChem化学物质编号:
329757203
NACRES:
NA.24

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等级

analytical standard

质量水平

200

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

应用

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

包装形式

neat

作用机制

DNA synthesis | interferes
cell wall synthesis | interferes
protein synthesis | interferes

SMILES字符串

[O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1

InChI

1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+

InChI key

NXFQHRVNIOXGAQ-YCRREMRBSA-N

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相关类别

一般描述

呋喃妥因是一种抗生素，能够有效对抗革兰氏阳性和阴性菌。该药主要用于治疗尿路感染。

应用

呋喃妥因已被用作高效液相色谱-电化学检测法测定牛奶中呋喃妥因含量的参考标准品。
有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险声明

H302,H317,H334

危险分类

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCH4891
BCCD2138
BCBZ5182
BCBT0937V

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Determination of nitrofurantoin in pharmaceutical preparations using flow injection-spectrophotometry.
Had H, et al.
Journal of the Association of Arab Universities for Basic and Applied Sciences, 24(1), 74-80 (2017)
Marta Veses-Garcia et al.
Frontiers in microbiology, 9, 1530-1530 (2018-07-26)
Achieving fast antimicrobial susceptibility results is a primary goal in the fight against antimicrobial resistance. Standard antibiotic susceptibility testing (AST) takes, however, at least a day from patient sample to susceptibility profile. Here, we developed and clinically validated a rapid
Brenda M Kazemier et al.
BMC pregnancy and childbirth, 12, 52-52 (2012-08-16)
The prevalence of asymptomatic bacteriuria (ASB) in pregnancy is 2-10% and is associated with both maternal and neonatal adverse outcomes as pyelonephritis and preterm delivery. Antibiotic treatment is reported to decrease these adverse outcomes although the existing evidence is of
Hedvig Nordeng et al.
Obstetrics and gynecology, 121(2 Pt 1), 306-313 (2013-01-25)
To estimate whether first-trimester exposure to nitrofurantoin is associated with increased malformation rates and, secondarily, to estimate whether exposure to nitrofurantoin is associated with increased rates of negative pregnancy outcomes and perinatal complications. We conducted a population-based cohort study using
Benjamin A Rogers et al.
Microbial drug resistance (Larchmont, N.Y.), 19(2), 100-103 (2013-01-22)
The New Delhi metallo-β-lactamase gene (bla(NDM-1)) has emerged as a worldwide concern among isolates of Enterobacteriaceae. Its epidemiology is been strongly associated with travel and healthcare on the Indian Subcontinent. We report two cases of urinary tract infection with Enterobacteriaceae
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