46648
吡喹酮
VETRANAL®, analytical standard
别名:
2-(环己基羰基)-1,2,3,6,7-11b-六氢-4H-吡嗪并-[2,1-a]-异喹啉-4-酮
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关于此项目
经验公式（希尔记法）:
C19H24N2O2
化学文摘社编号:
分子量:
312.41
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
259-559-6
Beilstein/REAXYS Number:
761557
MDL number:
产品名称
吡喹酮, VETRANAL®, analytical standard
InChI key
FSVJFNAIGNNGKK-UHFFFAOYSA-N
InChI
1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2
SMILES string
O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
antibiotic activity spectrum
parasites
application(s)
clinical testing
format
neat
mode of action
cell membrane | interferes
storage temp.
2-8°C
Quality Level
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Application
PZQ may be used as a reference standard for the determination for PZQ in:
- Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.
- Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.
- Tablet formulations by reversed phase (RP) HPLC with ultraviolet (UV) detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Chemical structure: quinolone
Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
Chromatographic separation of racemic praziquantel and its residual determination in perch by LC-MS/MS.
He L, et al.
Talanta, 174, 380-386 (2017)
Analysis of anthelmintics in surface water by ultra high performance liquid chromatography coupled to quadrupole linear ion trap tandem mass spectrometry.
Zrncic M, et al.
Chemosphere, 99, 224-232 (2014)
Study of praziquantel phytoremediation and transformation and its removal in constructed wetland.
Marsik P, et al.
Journal of Hazardous Materials, 323, 394-399 (2017)
A rapid stability indicating LC-method for determination of praziquantel in presence of its pharmacopoeial impurities.
Hashem H, et al.
Arabian Journal of Chemistry, 10, S35-S41 (2017)
Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots.
Meister I, et al.
Journal of Pharmaceutical and Biomedical Analysis, 118, 81-88 (2016)
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