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Merck
CN

46656

Supelco

泼尼松龙

VETRANAL®, analytical standard

别名:

1,4-孕甾二烯-11β,17α,21-三醇-3,20-二酮, 1-去氢氢化可的松, 1-去氢皮质醇, 11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮

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关于此项目

经验公式（希尔记法）:
C21H28O5
化学文摘社编号:
50-24-8
分子量:
360.44
Beilstein:
1354103
EC 号:
200-021-7
MDL编号:
MFCD00003649
UNSPSC代码:
41116107
PubChem化学物质编号:
329756614
NACRES:
NA.24

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等级

analytical standard

质量水平

100

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

240 °C (dec.) (lit.)

应用

forensics and toxicology
pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

OIGNJSKKLXVSLS-VWUMJDOOSA-N

基因信息

human ... NR3C1(2908)

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相关类别

一般描述

Prednisolone is classified under the corticosteroids class of compounds.

应用

Prednisolone may be used as an analytical standard for the determination of prednisolone in:
  • Human plasma by multivariate curve resolution-alternating least squares (MCR-ALS) technique combined with high performance liquid chromatography-diode array detection (HPLC-DAD).
  • Urine, blood and food matrices by solid-phase extraction (SPE) and LC coupled to tandem mass spectrometry (LC-MS/MS).
  • Surface water samples by SPE and ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QTOF) with electrospray ionization (ESI).
  • Bovine muscle samples by ESI-LC-MS/MS equipped with multiple reaction monitoring (MRM) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H360FD

危险分类

Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCG7680
BCBW5950

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Database-driven screening of South African surface water and the targeted detection of pharmaceuticals using liquid chromatography-High resolution mass spectrometry.
Wood TP, et al.
Environmental Pollution (Barking, Essex : 1987), 230, 453-462 (2017)
Handling of highly coeluted chromatographic peaks by multivariate curve resolution for a complex bioanalytical problem: Quantitation of selected corticosteroids and mycophenolic acid in human plasma.
Rezaei F, et al.
Talanta, 187, 1-12 (2018)
Quantification of doping compounds in faecal samples from racing pigeons, by liquid chromatography-tandem mass spectrometry.
Moreira FX, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1089, 33-42 (2018)
Simultaneous determination of residues of non-steroidal anti-inflammatory drugs and glucocorticosteroids in animal muscle by liquid chromatography-tandem mass spectrometry.
Jedziniak P, et al.
Food Analytical Methods, 9(6), 1837-1848 (2016)
Ádám Tölgyesi et al.
Journal of pharmaceutical and biomedical analysis, 145, 805-813 (2017-08-20)
Veterinary drugs containing synthetic anabolic steroid and nitroimidazole active agents are not allowed for their applications in livestock of the European Union (EU). This paper presents analyses of twelve selected steroids and six nitroimidazole antibiotics at low levels (1.56μg/L-4.95μg/L and
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