46698
6-丙基-2-硫尿嘧啶
VETRANAL®, analytical standard
别名:
2,3-二氢-6-丙基-2-硫代-4 (1 H )-嘧啶酮, 4-羟基-2-巯基-6-丙基嘧啶
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关于此项目
经验公式（希尔记法）:
C7H10N2OS
化学文摘社编号:
分子量:
170.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-103-2
Beilstein/REAXYS Number:
130039
MDL number:
产品名称
6-丙基-2-硫尿嘧啶, VETRANAL®, analytical standard
InChI key
KNAHARQHSZJURB-UHFFFAOYSA-N
InChI
1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
SMILES string
CCCC1=CC(=O)NC(=S)N1
grade
analytical standard
description
enzyme inhibitor
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
218-220 °C (lit.)
application(s)
clinical testing
format
neat
Quality Level
Gene Information
human ... DIO1(1733), TPO(7173)
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Si Wu et al.
Journal of pharmaceutical and biomedical analysis, 72, 109-114 (2012-11-14)
A serum metabonomic profiling method based on ultra-performance liquid chromatography/time-of-flight mass spectrometry (UHPLC/TOF-MS) was applied to investigate the metabolic changes in hypothyroid rats induced by propylthiouracil (PTU). With Significance Analysis of Microarray (SAM) for classification and selection of biomarkers, 13
Juneo F Silva et al.
Reproduction, fertility, and development, 24(7), 923-931 (2012-09-01)
The objective of this study was to evaluate fetal weight, histomorphometric changes and proliferative activity, apoptosis and angiogenesis of the placenta in rats with hypothyroidism. Thirty-six adult female rats were divided into two groups with 18 animals each: control and
Sarah V Lipchock et al.
The American journal of clinical nutrition, 98(4), 1136-1143 (2013-09-13)
Alleles of the receptor gene TAS2R38 are responsible in part for the variation in bitter taste perception of 6-n-propylthiouracil (PROP) and structurally similar compounds (eg, glucosinolates in cruciferous vegetables). At low concentrations, people with the PAV ("taster" amino acid sequence)
Min Chen et al.
Nature reviews. Nephrology, 8(8), 476-483 (2012-06-06)
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) refers to a group of potentially life-threatening autoimmune diseases. A recent development in this field is the recognition that certain drugs can induce AAV. Among these agents, the drug most often implicated in causing
R Thomas Zoeller et al.
Critical reviews in toxicology, 35(8-9), 771-781 (2006-01-19)
Because thyroid hormone is essential for normal brain development before and after birth, environmental chemicals that interfere with thyroid hormone signaling can adversely affect brain development. Adverse consequences of thyroid hormone insufficiency depend both on severity and developmental timing, indicating
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