46834
磺胺对甲氧嘧啶
VETRANAL®, analytical standard
别名:
5-甲氧基磺胺嘧啶, N1-(5-甲氧基嘧啶-2-基)磺胺
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关于此项目
经验公式（希尔记法）:
C11H12N4O3S
化学文摘社编号:
分子量:
280.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
211-480-8
Beilstein/REAXYS Number:
621130
MDL number:
产品名称
磺胺对甲氧嘧啶, VETRANAL®, analytical standard
InChI key
GPTONYMQFTZPKC-UHFFFAOYSA-N
InChI
1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
SMILES string
COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfameter may be used as a reference standard in the determination of sulfameter in water samples and natural animal casings using solid phase extraction with high-performance liquid chromatography coupled with an ultraviolet detector (SPR-HPLC-UV).
General description
Chemical structure: sulfonamide
Sulfameter is a long-acting sulfonamide, which is found to be effective on urinary and respiratory tract infections. It is often used for animal disease treatment and prevention.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
Quantitative analysis of sulfonamide residues in natural animal casings by HPLC.
Sun H, et al.
Chromatographia, 66(5-6), 333-337 (2007)
Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC-UV detection.
Sun L, et al.
Chemosphere, 77(10), 1306-1312 (2009)
Studies of sulfamethoxydiazine.
Chew HW, et al.
Clinical Pharmacology and Therapeutics, 6(3), 307-315 (1965)
J Horák et al.
Hepato-gastroenterology, 31(5), 199-200 (1984-10-01)
Two cases of severe sulfonamide liver injury are described. In one patient, fulminant liver failure developed after two days of taking sulfamethoxazole-trimethoprim. The patient was treated with resin hemoperfusion and recovered completely. Another patient became jaundiced after using sulfamethoxydiazine for
Yongjun Wu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 81(1), 544-547 (2011-07-29)
Sulfamethoxydiazine (SMD), which is often used for animal disease treatment, is harmful to human health. No SMD residue should be detected in food in some countries, such as USA and Japan. Therefore, it is significant to develop a high-throughput, high-sensitivity
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