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Merck
CN

49724

Supelco

丹酚酸 B

analytical standard

别名:

(2 S ,3 S )-4-[(1 E )-3-[(1 R )-1-羧基-2-（3,4-二羟基苯基）乙氧基]-3-氧代-1-丙烯-1-基]-2-（3,4-二羟基苯基）-2,3-二氢-7-羟基-3-苯并呋喃羧酸 3-[(1 R )-1-羧基-2-（3,4-二羟基苯基）乙基] 酯, 丹参酸 B, 丹芬酸 B, 紫草酸 B

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关于此项目

经验公式（希尔记法）:
C36H30O16
化学文摘社编号:
121521-90-2
分子量:
718.61
MDL编号:
MFCD23115783
UNSPSC代码:
85151701
PubChem化学物质编号:
329757512
NACRES:
NA.24

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等级

analytical standard

质量水平

100

方案

≥95.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c3O[C@@H]([C@@H](C(=O)O[C@H](Cc4ccc(O)c(O)c4)C(O)=O)c23)c5ccc(O)c(O)c5

InChI

1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31+,32-/m1/s1

InChI key

SNKFFCBZYFGCQN-VWUOOIFGSA-N

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相关类别

一般描述

Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease.
Salvianolic acid B is one of the main water soluble bioactive components of Salvia miltiorrhiza medicinal plant, the root of which is used in the treatment of dysmenorrhea, coronary heart disease, chronic renal failure, cerebrovascular disease, hypertension, and cytotoxicity against human tumor cell lines.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Salvianolic acid B may be used as an analytical reference standard for the quantification of the anayte in the roots of Salvia miltiorrhiza and other related Chinese medicines using chromatography techniques.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

This compound is commonly found in plants of the genus: salvia

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN5543
BCCM1718
BCCJ9596
BCCH9727
BCCG9796

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Isolation and purification of salvianolic acid A and salvianolic acid B from Salvia miltiorrhiza by high-speed counter-current chromatography and comparison of their antioxidant activity.
Sun Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(8-9), 733-737 (2009)
Yong-Xue Guo et al.
Journal of pharmaceutical and biomedical analysis, 43(4), 1249-1255 (2006-11-23)
The degradation of lithospermic acid B (LAB) was investigated as a function of buffer concentration, pH and temperature. Stability tests were performed using a stability-indicating high-performance liquid chromatography (HPLC) with UV-vis detection. The degradation followed pseudo-first-order kinetics under all experimental
Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC--DAD method
Liu H-A, et al.
Journal of Pharmaceutical and Biomedical Analysis, 41(1), 48-56 (2006)
Yong-Xue Guo et al.
Journal of pharmaceutical and biomedical analysis, 43(2), 435-439 (2006-09-05)
The hydrolytic kinetics of lithospermic acid B (LAB) extracted from the roots of Salvia miltiorrhiza (Chinese herb: danshen) was investigated by using reversed-phase high-performance liquid chromatography (HPLC) with UV-vis detection. The influences of initial drug concentration, pH and temperature on
Dae Gill Kang et al.
Phytotherapy research : PTR, 17(8), 917-920 (2003-09-19)
The roots of Salviae miltiorrhiza (RSM) have been traditionally used for treatment of hypertensive disease in China, Korea, and Japan. Bioassay guided fractionation and purification as assayed by angiotensin converting enzyme (ACE) inhibitory assay resulted in the isolation of lithospermic
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