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Merck
CN

49768

育亨宾 盐酸盐

analytical standard

别名:

17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride

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关于此项目

经验公式(希尔记法):
C21H26N2O3 · HCl
化学文摘社编号:
分子量:
390.90
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
200-600-4
MDL number:
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InChI key

PIPZGJSEDRMUAW-VJDCAHTMSA-N

InChI

1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24;/h2-5,12,15,17-19,22,24H,6-11H2,1H3;1H/t12-,15-,17-,18-,19+;/m0./s1

SMILES string

Cl.COC(=O)[C@H]1[C@@H](O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC12

grade

analytical standard

assay

≥98.0% (HPLC)

optical activity

[α]/D 100±5°, c = 1 in H2O

shelf life

limited shelf life, expiry date on the label

mp

288-290 °C (dec.) (lit.)

application(s)

food and beverages

format

neat

storage temp.

−20°C

Quality Level

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General description

Yohimbine is a major indole alkaloid typically extracted from the barks of Pausinystalia yohimbine, Corynanthe yohimbe, and Rauvolfia sepentina trees.

Application

Yohimbine hydrochloride may be used as an analytical standard for the determination of the analyte in dietary supplements by chromatography techniques.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Comparative analysis by HPLC-UV and capillary electrophoresis of dietary supplements for weight loss
Tero-Vescan A, et al.
Farmacia, 64(5), 699-705 (2016)
Case study: two fatal case reports of acute yohimbine intoxication
Anderson C, et al.
Journal of Analytical Toxicology, 37(8), 611-614 (2013)
A simple electrochemical sensor based on graphene nanoplatelets modified glassy carbon electrode (GrNPs/GCE) for highly sensitive detection of yohimbine (YOH)
Rodsud S and Limbut W
Journal of the Electrochemical Society, 166(10), B771-B771 (2019)
Gas chromatographic determination of yohimbine in commercial yohimbe products
Betz JM, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 78(5), 1189-1194 (1995)
Pharmaceutical quantities of yohimbine found in dietary supplements in the USA
Cohen PA, et al.
Drug Testing and Analysis, 8(3-4), 357-369 (2016)

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