53541
妥布特罗 盐酸盐
VETRANAL®, analytical standard
别名:
2-叔丁氨基-1-(2-氯苯基)乙醇 盐酸盐
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关于此项目
经验公式（希尔记法）:
C12H18ClNO · HCl
化学文摘社编号:
分子量:
264.19
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
妥布特罗 盐酸盐, VETRANAL®, analytical standard
InChI
1S/C12H18ClNO.ClH/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13;/h4-7,11,14-15H,8H2,1-3H3;1H
SMILES string
Cl.CC(C)(C)NCC(O)c1ccccc1Cl
InChI key
RSLNRVYIRDVHLY-UHFFFAOYSA-N
grade
analytical standard
product line
VETRANAL®
assay
≥98.0% (HPLC)
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
Quality Level
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
盐酸妥洛特罗可作为参考标准品，通过气相色谱-串联质谱（GC-MS-MS）测定牛肝匀浆和尿液样品中盐酸妥洛特罗的浓度。
General description
Supelco MIP SPE柱的标准品。有关更多信息，请索要Supelco文献T407075、T706019、T706030、T706020
盐酸妥洛特罗是一种拟交感神经胺，具有支气管扩张剂的活性。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
此项目有
Tetsuya Abe et al.
Pulmonary pharmacology & therapeutics, 24(5), 617-624 (2011-06-22)
The addition of transdermal tulobuterol (Tulo) to inhaled tiotropium bromide (Tio) produced beneficial effects on spirometry-assessed parameters of respiratory function, disease-related symptoms and quality of life in patients with chronic obstructive pulmonary disease (COPD). To compare the effects of Tio
Ki-Seok Kim et al.
Colloids and surfaces. B, Biointerfaces, 76(2), 404-409 (2009-12-26)
In this work, porous poly(epsilon-caprolactone) (PCL)/Eudragit RS 100 (ERS-100) microcapsules containing tulobuterol base as a model drug were prepared by a solvent evaporation method and the effect of the quaternary ammonium groups of ERS-100 on the release behaviors of the
Tetsuo Watanabe et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(10), 1483-1492 (2011-10-04)
The purpose of this study was to compare the transdermal transfer profiles of brand and generic tulobuterol patch formulations and to evaluate possible changes of in vivo kinetics resulting from increased transdermal transfer by means of pharmacokinetic analysis using reported
Ki-Seok Kim et al.
Colloids and surfaces. B, Biointerfaces, 80(2), 240-246 (2010-07-14)
pH sensitive Pluronic F127 (PF127)/poly(acrylic acid) (PAAc) hydrogels containing tulobuterol-loaded silica were prepared with PF127 content. The effects of the PF127 content and silica on the sustained release behaviors of the PAAc hydrogels were investigated. The results showed that the
Chiyohiko Shindoh et al.
The Tohoku journal of experimental medicine, 218(4), 271-278 (2009-07-30)
Tulobuterol, a sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. Because diaphragm muscle weakness (i.e. decrease of contraction) is a feature of bronchial asthma and sepsis, we examined the in vitro and in vivo effects of
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