产品名称
N-月桂酰肌氨酸, purum p.a., ≥98.0% (GC)
description
anionic
Quality Level
grade
purum p.a.
assay
≥98.0% (GC)
mol wt
271.40 g/mol
technique(s)
protein quantification: suitable
impurities
≤0.2% water
ign. residue
≤0.1%
mp
45-50 °C
anion traces
chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤20 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤10 mg/kg, K: ≤70 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤20 mg/kg
functional group
amide, carboxylic acid
SMILES string
CCCCCCCCCCCC(=O)N(C)CC(O)=O
InChI
1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)
InChI key
BACYUWVYYTXETD-UHFFFAOYSA-N
General description
N-月桂酰肌氨酸(N-十二烷酰基-N-甲基甘氨酸,Sarkosyl L,LS)是一种阴离子表面活性剂。已经研究了其在小鼠模型中对单纯疱疹病毒2型(HSV-2)阴道内感染的杀伤作用。
Application
N-月桂酰肌氨酸可用作透皮制剂中的透皮增强剂,因为它能够增强皮肤角质层脂质结构的流动性†
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 285(29), 22221-22231 (2010-04-21)
More than 100 different mutations in Cu,Zn-superoxide dismutase (SOD1) are linked to a familial form of amyotrophic lateral sclerosis (fALS). Pathogenic mutations facilitate fibrillar aggregation of SOD1, upon which significant structural changes of SOD1 have been assumed; in general, however
Yeu-Chun Kim et al.
International journal of pharmaceutics, 352(1-2), 129-138 (2007-12-15)
To develop formulations for transdermal drug delivery, this study tested the hypothesis that the anionic surfactant, N-lauroylsarcosine (NLS), and ethanol synergistically increase skin permeability by increasing the fluidity of stratum corneum lipid structure. Skin permeability experiments showed that transdermal delivery
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 286(21), 18664-18672 (2011-04-02)
The transactivation response element (TAR) DNA-binding protein-43 (TDP-43) is a nuclear protein that normally regulates transcription and splicing. Abnormal accumulation of insoluble inclusions containing TDP-43 has been recently reported in the affected tissues of amyotrophic lateral sclerosis (ALS) patients. Here
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 61739-25G | 04061835555338 |
| 61739-5G | 04061832700618 |

