主要文件

查看所有文档

63184

伊红-5-马来酰亚胺

Name: 伊红-5-马来酰亚胺
Brand: SIAL

suitable for fluorescence, ≥93% (HPLC)

别名:

EMA, 伊红-5-马来酰亚胺

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₂₄H₉Br₄NO₇

化学文摘社编号:

150322-02-4

分子量:

742.95

NACRES:

NA.32

PubChem Substance ID:

329759808

UNSPSC Code:

12352207

MDL number:

MFCD07437936

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

100

assay

≥93% (HPLC)

form

powder

mol wt

742.95 g/mol

color

light orange to dark orange, light red

fluorescence

λ_ex 524 nm; λ_em 545 nm (after derivatization with 2-mercaptoethanol)

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5cc(ccc45)N6C(=O)C=CC6=O)c1Br

InChI

1S/C24H9Br4NO7/c25-13-6-11-21(17(27)19(13)32)35-22-12(7-14(26)20(33)18(22)28)24(11)10-2-1-8(5-9(10)23(34)36-24)29-15(30)3-4-16(29)31/h1-7,32-33H

InChI key

YRCLWXRIEYQTAV-UHFFFAOYSA-N

说明

General description

5-马来酰亚胺-伊红，也称为 EMA 或伊红-5-马来酰亚胺，是一种荧光结合剂。5-马来酰亚胺-伊红结合试验可测量 EMA 标记细胞减少的平均通道荧光（MCF）读数。

Application

伊红-5-马来酰亚胺已被用作人红细胞带 3 蛋白的荧光探针。它被广泛用作实验室诊断探针，以通过流式细胞术检测遗传性球形红细胞增多症（HS）。伊红-5-马来酰亚胺结合试验已用于分析阿勒替尼（一线治疗）对于变性淋巴瘤激酶（ALK）的效果。

Other Notes

三重探针。测量蛋白质在溶液和膜中的旋转扩散，包括肌球蛋白和丙酮酸脱氢酶

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Rotational motions of myosin heads in myofibril studied by phosphorescence anisotropy decay measurements.

S Ishiwata et al.

The Journal of biological chemistry, 262(17), 8314-8317 (1987-06-15)

We studied the rotational Brownian motions of myosin heads, of which the sulfhydryl group was selectively labeled with the triplet probe 5-eosinylmaleimide, in myofibril by using flash-induced phosphorescence anisotropy decay measurements. The anisotropy decay curve under relaxing conditions consisted of

Toward the harmonization of result presentation for the eosin-5'-maleimide binding test in the diagnosis of hereditary spherocytosis.

Linda Hunt et al.

Cytometry. Part B, Clinical cytometry, 88(1), 50-57 (2014-09-18)

The eosin-5'-maleimide (EMA) Binding test measures reduced mean channel fluorescence (MCF) reading of EMA-labeled red cells (EMA-RBCs) from patients with hereditary spherocytosis (HS). Reporting test results can be either in the actual MCF reading or as a ratio by normalization

Use of capillary blood to diagnose hereditary spherocytosis.

Renée L Crisp et al.

Pediatric blood & cancer, 59(7), 1299-1301 (2012-04-11)

We studied 31 children with hemolytic anemia, or with positive family history for hereditary spherocytosis (HS), to assess the reliability of capillary blood samples for the diagnosis. HS was diagnosed in 20 patients. Cryohemolysis (CH) was positive in 94% and

查看所有相关文献

全球贸易项目编号

货号	GTIN
A3412-5G	04061832489384
A3412-10G	04061833360835
A3412-1G	04061833360842
63184-10MG	04061832721255
63184-25MG	04061833277751