63406
丙二酸甲酯酰氯
purum, ≥97.0% (AT)
别名:
甲基丙二酰氯
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关于此项目
线性分子式:
CH3OCOCH2COCl
化学文摘社编号:
分子量:
136.53
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
253-540-6
Beilstein/REAXYS Number:
1754078
MDL number:
Assay:
≥97.0% (AT)
InChI key
UTBCRHAMJFMIIR-UHFFFAOYSA-N
InChI
1S/C4H5ClO3/c1-8-4(7)2-3(5)6/h2H2,1H3
SMILES string
COC(=O)CC(Cl)=O
grade
purum
assay
≥97.0% (AT)
Quality Level
bp
57-59 °C/12 mmHg (lit.)
density
1.273 g/mL at 25 °C (lit.)
functional group
acyl chloride, ester
storage temp.
2-8°C
Application
Methyl malonyl chloride can be used in the synthesis of methyl 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-one-6-carboxylates and 6-carboxamides, which can act like HIV integrase strand transfer inhibitors. It can also be used in the synthesis of Strychnos alkaloids like (-)-leuconicine A and (-)-leuconicine B.
Disclaimer
储存中可能变黄
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
176.0 °F - closed cup
flash_point_c
80 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
"Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy [1, 3] thiazolo [5, 4-b]pyridin-5 (4H)-ones"
Boros.EE, et al.
Bioorganic & Medicinal Chemistry, 16(21), 5668-5672 (2006)
"Total synthesis of (-)-leuconicine A and B"
Sirasani G and Andrade.BR
Organic Letters, 13(17), 4736-4737 (2011)
Elif Okutan et al.
Journal of fluorescence, 26(6), 2333-2343 (2016-11-01)
Colorimetric fluorescent chemosensors 4 and 5 based on mono- and di- styryl borondipyrromethenes (BODIPY) linked methyl malonyl were designed for detection of hemoglobin (HgB). Their sensing behavior toward various analytes (Br
实验方案
Photometric determination with Cuprizon subsequent to acid mineralisation
酸矿化后使用 Cuprizon 进行光度测定
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