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Merck
CN

65692

1-甲氧基-2-丙醇

greener alternative

analytical standard

别名:

丙二醇单甲醚, 丙二醇甲醚

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关于此项目

线性分子式:
CH3CH(OH)CH2OCH3
化学文摘社编号:
分子量:
90.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-539-1
Beilstein/REAXYS Number:
1731270
MDL number:
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产品名称

1-甲氧基-2-丙醇, analytical standard

InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

SMILES string

CC(O)COC

grade

analytical standard

vapor density

3.12 (vs air)

vapor pressure

10.9 mmHg ( 25 °C)

assay

≥99.7% (GC)

autoignition temp.

532 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

13.8 %

Quality Level

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.403 (lit.)
n20/D 1.403

bp

118-119 °C (lit.)

density

0.916 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

greener alternative category

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Application

1-甲氧基-2-丙醇可用作分析标准品,用于通过各种色谱技术测定人和动物生物样品 中的分析物。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。

General description

1-甲氧基-2-丙醇是最常见的丙烯基乙二醇醚之一,其有望用于多种工业和商业应用,主要用作油漆、清漆、油墨等的成分。它也是短链乙二醇醚的效力较低的替代品。

Features and Benefits

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

pictograms

FlameExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

target_organs

Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

93.2 °F - closed cup

flash_point_c

34 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J Laitinen et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(1), 93-98 (1997-06-20)
At the end of a workweek 23 silkscreen printers gave a urine sample for capillary gas chromatographic analysis for 1,2-propanediol. The mean concentration was 2.52 (S.D. 2.01) mmol mol creatinine(-1) (median=1.76, n=23). The urinary excretion of 1,2-propanediol was linearly dependent
Gas-chromatographic determination of propylene-and diethylene glycol ethers in urine
Hubner B, et al.
Fresenius Journal of Analytical Chemistry, 342(9), 746-748 (1992)
A biological monitoring study of 1-methoxy-2-propanol: analytical method development and a human volunteer study
Jones K, et al.
The Science of the Total Environment, 199(1-2), 23-30 (1997)
N F Ferrala et al.
Journal of chromatography. B, Biomedical applications, 660(2), 291-296 (1994-10-14)
A method utilizing capillary GC and flame ionization detection was developed for the simultaneous determination of 1-methoxy-2-propanol (propylene glycol monomethyl ether; PGME) and its metabolite 1,2-propanediol (propylene glycol; PG) in rat and mouse plasma. The calibration graphs for rat and
S R Vink et al.
Regulatory toxicology and pharmacology : RTP, 58(1), 64-71 (2010-04-17)
REACH requests the exploration of alternative strategies for hazard identification before resorting to (in vivo) testing. Here, we combined read-across as non-testing strategy with a tiered exposure assessment for the risk characterisation of 1-methoxypropan-2-ol (PGME) as a representative for phase-in

商品

Learn about analyzing organic volatile impurities (OVIs) in pharmaceuticals using SH-GC, focusing on suitable solvents and ensuring compliance.

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