InChI
1S/C3H4O2/c1-3(5)2-4/h2H,1H3
SMILES string
[H]C(=O)C(C)=O
InChI key
AIJULSRZWUXGPQ-UHFFFAOYSA-N
grade
technical
concentration
~40% in H2O
density
1.19 g/mL at 20 °C
functional group
aldehyde, ketone
storage temp.
2-8°C
Quality Level
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General description
甲基乙二醛是糖酵解的一种有毒内源性副产物。它是一种反应性二羰基化合物,可促进蛋白质的非酶糖基化作用以产生不可逆的高级糖基化终产物,从而导致蛋白质的交联或降解。
Application
甲基乙二醛溶液可用于细胞毒性研究。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Al?Balas Q A, et al.
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Ogasawara Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1029, 102-105 (2016)
Potential Neuroprotective and Anti-Apoptotic Properties of a Long-Lasting Stable Analog of Ghrelin: an In Vitro Study Using SH-SY5Y Cells.
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The Journal of investigative dermatology, 135(2), 589-598 (2014-09-04)
Glyoxalase I (GLO1) is a methylglyoxal detoxification enzyme being implicated in the progression of multiple malignancies. However, currently, the role of GLO1 in human nonmelanoma skin tumors remains unclear. To explore the expression of GLO1 in cutaneous neoplasms and its
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Proceedings of the National Academy of Sciences of the United States of America, 111(13), 4940-4945 (2014-02-26)
Age-associated dementia and Alzheimer's disease (AD) are currently epidemic. Neither their cause nor connection to the metabolic syndrome (MS) is clear. Suppression of deacetylase survival factor sirtuin 1 (SIRT1), a key host defense, is a central feature of AD. Age-related
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