67176
(R)-2-哌嗪羧酸 二盐酸盐
≥98.0%
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关于此项目
经验公式（希尔记法）:
C5H10N2O2 · 2HCl
化学文摘社编号:
分子量:
203.07
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥98.0% (T)
≥98.0%
表单
solid
旋光性
[α]20/D +5±1°, c = 1% in H2O
SMILES字符串
Cl.Cl.OC(=O)[C@H]1CNCCN1
InChI
1S/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H/t4-;;/m1../s1
InChI key
WNSDZBQLMGKPQS-RZFWHQLPSA-N
应用
(R)-2-Piperazinecarboxylic acid dihydrochloride can be used as a starting material for the synthesis of (R)-enantiomers of anthramycin analogs, which are potential antiproliferative agents. It can also be employed in the preparation of piperazinemethanol chiral ligands, which can be utilized in the enantioselective borane reduction of aromatic ketones, ketimine, and oxime ether.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Enantiomerically pure 2-piperazinemethanols as novel chiral ligands of oxazaborolidine catalysts in enantioselective borane reductions
Inoue T, et al.
Tetrahedron Letters, 40(29), 5379- 5382 (1999)
Novel (S)-1, 3, 4, 12a-tetrahydropyrazino [2, 1-c][1, 4] benzodiazepine-6, 12 (2H, 11H)-dione derivatives: Selective inhibition of MV-4-11 biphenotypic b myelomonocytic leukemia cells? growth is accompanied by reactive oxygen species overproduction and apoptosis
Mieczkowski A, et al.
Bioorganic & medicinal chemistry letters, 28(4), 618- 625 (2018)
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