67176
(R)-2-哌嗪羧酸 二盐酸盐
≥98.0%
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关于此项目
经验公式（希尔记法）:
C5H10N2O2 · 2HCl
化学文摘社编号:
分子量:
203.07
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
产品名称
(R)-2-哌嗪羧酸 二盐酸盐, ≥98.0%
InChI
1S/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H/t4-;;/m1../s1
SMILES string
Cl.Cl.OC(=O)[C@H]1CNCCN1
InChI key
WNSDZBQLMGKPQS-RZFWHQLPSA-N
assay
≥98.0% (T)
≥98.0%
form
solid
optical activity
[α]20/D +5±1°, c = 1% in H2O
Quality Level
Application
(R)-2-Piperazinecarboxylic acid dihydrochloride can be used as a starting material for the synthesis of (R)-enantiomers of anthramycin analogs, which are potential antiproliferative agents. It can also be employed in the preparation of piperazinemethanol chiral ligands, which can be utilized in the enantioselective borane reduction of aromatic ketones, ketimine, and oxime ether.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Novel (S)-1, 3, 4, 12a-tetrahydropyrazino [2, 1-c][1, 4] benzodiazepine-6, 12 (2H, 11H)-dione derivatives: Selective inhibition of MV-4-11 biphenotypic b myelomonocytic leukemia cells? growth is accompanied by reactive oxygen species overproduction and apoptosis
Mieczkowski A, et al.
Bioorganic & medicinal chemistry letters, 28(4), 618- 625 (2018)
Enantiomerically pure 2-piperazinemethanols as novel chiral ligands of oxazaborolidine catalysts in enantioselective borane reductions
Inoue T, et al.
Tetrahedron Letters, 40(29), 5379- 5382 (1999)
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