67403
Cirsilineol
analytical standard
别名:
4′,5-Dihydroxy-3′,6,7-trimethoxyflavone, 6-Methoxyluteolin 3′,7-dimethyl ether, Anisomelin, Eupatrin, Fastigenin
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关于此项目
经验公式(希尔记法):
C18H16O7
化学文摘社编号:
分子量:
344.32
Beilstein:
1355108
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥95.0% (HPLC and enzymatic)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
food and beverages
包装形式
neat
SMILES字符串
COc1cc(ccc1O)C2=CC(=O)c3c(O)c(OC)c(OC)cc3O2
InChI
1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
InChI key
VKOSQMWSWLZQPA-UHFFFAOYSA-N
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一般描述
Cirsilineol is a bioactive flavone isolated from the herb of Artemisia vestita Wall., widely used to treat a variety of inflammatory conditions such as contact dermatitis, rheumatoid arthritis and sepsis. Cirsilineol exhibits anti-proliferative activity, which is used against different cancer cells by inducing apoptosis.
应用
Cirsilineol may be used as an analytical reference standard for the quantification of the analyte in vervain samples and extracts of Teucrium polium using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Chun-nian He et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 30(10), 761-763 (2005-08-04)
To study the chemical constituents of Anoectochilus roxburghii. Silica gel and sephadex LH-20 column chromotography were used in the isolation from the ethanol extracts of the whole plant, the compounds were determined on the basis of various modern spectroscopic analysis
H J Heo et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 8(3), 194-201 (2001-10-26)
Amyloid beta protein (Abeta)-induced free radical-mediated neurotoxicity is a leading hypothesis as a cause of Alzheimer's disease (AD). Abeta increased free radical production and lipid peroxidation in PC12 nerve cells, leading to apoptosis and cell death. The effect of 4',5-dihydroxy-3',6,7-trimethoxyflavone
[Flavones isolated from Thymus carnosus Boiss].
E Maruhenda et al.
Annales pharmaceutiques francaises, 45(6), 467-470 (1987-01-01)
HPLC and UV-spectrophotometry analysis of flavonoids in spray-dried and freez-dried extracts of Teucrium polium L.(Lamiaceae)
Stefkov G, et al.
Macedonian pharmaceutical bulletin, 47(11), 39-44 (2012)
Yang Sun et al.
Biochemical pharmacology, 79(2), 229-238 (2009-08-25)
Regulation of signal transducer and activator of transcription (STAT) 1 signaling is being explored as a new approach to the treatment of inflammatory bowel diseases. However, few chemicals have been reported to inhibit IFN-gamma/STAT1 signaling for Crohn's disease therapy. In
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