67403
Cirsilineol
analytical standard
别名:
4′,5-Dihydroxy-3′,6,7-trimethoxyflavone, 6-Methoxyluteolin 3′,7-dimethyl ether, Anisomelin, Eupatrin, Fastigenin
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关于此项目
经验公式（希尔记法）:
C18H16O7
化学文摘社编号:
分子量:
344.32
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1355108
InChI
1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
SMILES string
COc1cc(ccc1O)C2=CC(=O)c3c(O)c(OC)c(OC)cc3O2
InChI key
VKOSQMWSWLZQPA-UHFFFAOYSA-N
grade
analytical standard
assay
≥95.0% (HPLC and enzymatic)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
Quality Level
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General description
Cirsilineol is a bioactive flavone isolated from the herb of Artemisia vestita Wall., widely used to treat a variety of inflammatory conditions such as contact dermatitis, rheumatoid arthritis and sepsis. Cirsilineol exhibits anti-proliferative activity, which is used against different cancer cells by inducing apoptosis.
Application
Cirsilineol may be used as an analytical reference standard for the quantification of the analyte in vervain samples and extracts of Teucrium polium using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Gjoshe Stefkov et al.
Pharmaceutical biology, 49(9), 885-892 (2011-05-31)
The main objective of the study was to investigate the biochemical mechanism of the antidiabetic activities of the dry extracts of Teucrium polium L. ssp. capitatum (L.) Arcangeli (Lamiaceae), from Republic of Macedonia, traditionally used to treat diabetes. Aerial parts
Yang Sun et al.
Biochemical pharmacology, 79(2), 229-238 (2009-08-25)
Regulation of signal transducer and activator of transcription (STAT) 1 signaling is being explored as a new approach to the treatment of inflammatory bowel diseases. However, few chemicals have been reported to inhibit IFN-gamma/STAT1 signaling for Crohn's disease therapy. In
[Flavones isolated from Thymus carnosus Boiss].
E Maruhenda et al.
Annales pharmaceutiques francaises, 45(6), 467-470 (1987-01-01)
Chun-nian He et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 30(10), 761-763 (2005-08-04)
To study the chemical constituents of Anoectochilus roxburghii. Silica gel and sephadex LH-20 column chromotography were used in the isolation from the ethanol extracts of the whole plant, the compounds were determined on the basis of various modern spectroscopic analysis
Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway
Sheng X, et al.
The Journal of Pharmacy and Pharmacology, 60(11), 39-44 (2008)
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