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Merck
CN

67805

Supelco

艾地苯醌

analytical standard

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关于此项目

经验公式(希尔记法):
C19H30O5
化学文摘社编号:
分子量:
338.44
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥97.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

包装形式

neat

SMILES字符串

O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChI key

JGPMMRGNQUBGND-UHFFFAOYSA-N

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应用

有关合适的仪器技术的更多信息,请参阅产品的分析证书。想要获得更多支持,请联系技术服务部。

生化/生理作用

一种短链辅酶 Q 类似物,可通过介导电子从 N2 转移到氧来增强超氧化物的形成。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Caterina Tonon et al.
Expert opinion on pharmacotherapy, 9(13), 2327-2337 (2008-08-20)
Friedreich's ataxia is an autosomal recessive neurodegenerative disease where impaired mitochondrial function and excessive production of free radicals play a central pathogenetic role. Idebenone, a synthetic analogue of coenzyme Q, is a powerful antioxidant that was first administrated to Friedreich's
Esfandiar J Sabet-Peyman et al.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 32(1), 54-57 (2012-01-25)
A 31-year-old woman developed subacute bilateral visual loss over a 2-week period. Two months later, the diagnosis of Leber hereditary optic neuropathy (LHON) 11778/ND4 was established and the patient was treated with 900 mg of idebenone daily. Over the ensuing
Claudia Carbone et al.
Expert opinion on drug delivery, 9(11), 1377-1392 (2012-10-23)
Idebenone (IDE) is an antioxidant compound, structurally related to coenzyme Q10. Its therapeutic potential is growing in different application areas, as demonstrated by the number of experimental works and patents produced in very recent years. Cyclodextrin inclusion complexes, liposomes, microemulsions
M Suno et al.
Archives of gerontology and geriatrics, 8(3), 299-305 (1989-05-01)
The effects of idebenone on the swelling of rat brain mitochondria were studied. When FeCl3 was added to a mitochondrial suspension, a pronounced mitochondrial swelling occurred accompanied by the production of lipid peroxide; the two phenomena were closely correlated (r
Idebenone - monograph.
Alternative medicine review : a journal of clinical therapeutic, 6(1), 83-86 (2001-02-24)

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