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Merck
CN

68300

Tazobactam sodium salt

analytical standard

别名:

CL-298741, YTR-830H, [2S-(2α, 3β, 5α)]-3-Methyl-7-oxo-3(1H,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide

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关于此项目

经验公式(希尔记法):
C10H11N4NaO5S
化学文摘社编号:
分子量:
322.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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产品名称

Tazobactam sodium salt, analytical standard

InChI

1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1

SMILES string

[Na+].C[C@]2(Cn1ccnn1)[C@@H](N3[C@@H](CC3=O)S2(=O)=O)C([O-])=O

InChI key

RFMIKMMOLPNEDG-QVUDESDKSA-M

grade

analytical standard

assay

≥98.0% (HPLC)

optical activity

[α]/D 144±4°, c = 0.1 in H2O

shelf life

limited shelf life, expiry date on the label

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

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Application

Tazobactam sodium may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by reversed-phase high-performance liquid chromatography.

General description

Tazobactam sodium is the sodium salt of the β-lactamase inhibitor antibiotic, tazobactam. It is a semisynthetic parenteral penicillin which can be combined with piperacillin and ceftolozane drugs for treating a variety of infections.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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RP-HPLC method for simultaneous estimation of cefepime hydrochloride and tazobactam sodium in bulk and pharmaceuticals
Tamboli SR and Patil DD
Journal of Chemistry, 2013(1), 127-131 (2013)
RP-HPLC method for simultaneous estimation of cefepime hydrochloride and tazobactam sodium in bulk and pharmaceuticals
Tamboli SR and Patil DD
Journal of Chemistry, 2013(4), 543-543 (2013)
Stability indicating RP-HPLC method for the estimation of ceftazidime pentahydrate and tazobactam sodium in bulk and dosage forms
Amareswari S, et al.
Indian Journal of Pharmaceutical and Biological Research, 1(4), 543-543 (2013)
Simultaneous determination of piperacillin and tazobactam in pharmaceutical formulations by RP-HPLC method
Veni KRP, et al.
Journal of Pharmacy Research, 7(1), 127-131 (2013)

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