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经验公式(希尔记法):
C10H11N4NaO5S
化学文摘社编号:
分子量:
322.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
Tazobactam sodium salt, analytical standard
InChI
1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
SMILES string
[Na+].C[C@]2(Cn1ccnn1)[C@@H](N3[C@@H](CC3=O)S2(=O)=O)C([O-])=O
InChI key
RFMIKMMOLPNEDG-QVUDESDKSA-M
grade
analytical standard
assay
≥98.0% (HPLC)
optical activity
[α]/D 144±4°, c = 0.1 in H2O
shelf life
limited shelf life, expiry date on the label
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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Application
Tazobactam sodium may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by reversed-phase high-performance liquid chromatography.
General description
Tazobactam sodium is the sodium salt of the β-lactamase inhibitor antibiotic, tazobactam. It is a semisynthetic parenteral penicillin which can be combined with piperacillin and ceftolozane drugs for treating a variety of infections.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
RP-HPLC method for simultaneous estimation of cefepime hydrochloride and tazobactam sodium in bulk and pharmaceuticals
Tamboli SR and Patil DD
Journal of Chemistry, 2013(1), 127-131 (2013)
RP-HPLC method for simultaneous estimation of cefepime hydrochloride and tazobactam sodium in bulk and pharmaceuticals
Tamboli SR and Patil DD
Journal of Chemistry, 2013(4), 543-543 (2013)
Stability indicating RP-HPLC method for the estimation of ceftazidime pentahydrate and tazobactam sodium in bulk and dosage forms
Amareswari S, et al.
Indian Journal of Pharmaceutical and Biological Research, 1(4), 543-543 (2013)
Simultaneous determination of piperacillin and tazobactam in pharmaceutical formulations by RP-HPLC method
Veni KRP, et al.
Journal of Pharmacy Research, 7(1), 127-131 (2013)
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