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Merck
CN

68909

番泻苷A

analytical standard

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关于此项目

经验公式（希尔记法）:
C42H38O20
化学文摘社编号:
81-27-6
分子量:
862.74
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329761216
EC Number:
201-339-9
Beilstein/REAXYS Number:
5723746
MDL number:
MFCD00151527

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InChI key

IPQVTOJGNYVQEO-GTCVFCFLSA-N

InChI

1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42?/m1/s1

SMILES string

OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(cc(O)c8C(=O)c23)C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O

grade

analytical standard

assay

≥96.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

Quality Level

100

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相关类别

General description

Sennoside A 是一种羟基蒽糖苷，通常存在于含有决明子叶的聚醚配方中，用于治疗便秘。

Application

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCK5929
BCCJ3940
BCCF3621
BCCD1720
BCBZ8154

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Status of sennosides content in various Indian herbal formulations: method standardization by HPTLC
Aktar W, et al.
Bangladesh Journal of Pharmacology, 3, 64-68 (2008)
Acute generalized exanthematous pustulosis caused by sennoside in a patient with multiple myeloma.
K Sugita et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 22(4), 517-519 (2008-03-28)
Manuk N Manukyan et al.
Surgical laparoscopy, endoscopy & percutaneous techniques, 21(2), 90-93 (2011-04-08)
The aim of this study is to assess 2 different bowel-cleansing agents. The patients were prospectively randomized to 2 arms of sodium phosphate versus Sennoside A+B calcium preparation. Laboratory assessment, body weight, height, and vital signs were obtained at baseline
Acute hemorrhagic colitis following administration of sennosides for colon cleansing.
Burhan Ozdil et al.
The Annals of pharmacotherapy, 44(4), 770-771 (2010-03-25)
Philippa Helen Hawley et al.
Journal of palliative medicine, 11(4), 575-581 (2008-05-06)
Constipation is a common and distressing condition in patients with cancer, especially those taking opioid analgesics. Many institutions prevent and treat constipation with titrated laxatives, which is known as a bowel protocol. An effective and well-tolerated bowel protocol is a
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