70162
萘啶酸
≥99.0% (T)
别名:
1,4-二氢-1-乙基-7-甲基-1,8-萘啶-4-酮-3-羧酸, 1-乙基-1,4-二氢-7-甲基-4-氧代-1,8-萘啶-3-羧酸
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关于此项目
经验公式（希尔记法）:
C12H12N2O3
化学文摘社编号:
分子量:
232.24
EC Number:
206-864-7
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
750515
assay
≥99.0% (T)
mp
227-229 °C (lit.), 228-230 °C
solubility
chloroform: 20 mg/mL, clear
mode of action
DNA synthesis | interferes, enzyme | inhibits
SMILES string
CCN1C=C(C(O)=O)C(=O)c2ccc(C)nc12
InChI
1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)
InChI key
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
General description
Chemical structure: quinolone
Other Notes
细菌 DNA 合成抑制剂
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Studies on the mode of action of nalidixic acid.
A M Pedrini et al.
European journal of biochemistry, 25(2), 359-365 (1972-02-15)
Christopher M Parry
Transactions of the Royal Society of Tropical Medicine and Hygiene, 98(7), 413-422 (2004-05-13)
Multidrug-resistant (MDR) Salmonella Typhi (resistant to chloramphenicol, ampicillin, and trimethoprim-sulphamethoxazole) and isolates with reduced susceptibility to fluoroquinolones (indicated by resistance to nalidixic acid, NaR) have caused epidemics and become endemic in southern Viet Nam during the 1990s. Short courses of
Robert J Commons et al.
The Medical journal of Australia, 196(5), 332-336 (2012-03-22)
To determine incidence and trends in antibiotic resistance in Australian Salmonella enterica subspecies enterica serovars Typhi (S. Typhi) and Paratyphi (S. Paratyphi) isolates over the past 26 years. A retrospective analysis of consecutive microbiologically confirmed enteric fever isolates. All S.