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Merck
CN

73137

2,2-二甲氧基丙烷

analytical standard

别名:

丙酮缩二甲醇

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关于此项目

线性分子式:
(CH3)2C(OCH3)2
化学文摘社编号:
分子量:
104.15
UNSPSC Code:
41116107
NACRES:
NA.02
PubChem Substance ID:
EC Number:
201-056-0
Beilstein/REAXYS Number:
635678
MDL number:
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产品名称

2,2-二甲氧基丙烷, analytical standard

InChI

1S/C5H12O2/c1-5(2,6-3)7-4/h1-4H3

InChI key

HEWZVZIVELJPQZ-UHFFFAOYSA-N

SMILES string

COC(C)(C)OC

grade

analytical standard

vapor density

3.59 (vs air)

vapor pressure

60 mmHg ( 15.8 °C)

assay

≥99.4% (GC)

shelf life

limited shelf life, expiry date on the label

expl. lim.

31 %, 58 °F
6 %, 27 °F

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.378 (lit.)
n20/D 1.378

bp

79-81 °C
83 °C (lit.)

density

0.847 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

Quality Level

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Application

2,2-Dimethoxypropane may be used as an analytical standard for the determination of the analyte in biological samples by headspace gas chromatography-mass spectrometry (HS-GC/MS) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

2,2-Dimethoxypropane is an organic compound, which may be used as a protecting agent in the process of the synthesis of structurally related alkaloids like narciclasine and lycoricidine using phenylbromide as the starting material.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

14.0 °F - closed cup

flash_point_c

-10 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Quantitative determination of n-propane, iso-butane, and n-butane by headspace GC-MS in intoxications by inhalation of lighter fluid
Bouche MPLA, et al.
Journal of Analytical Toxicology, 26(1), 35-42 (2002)
Total Synthesis of Lycoricidine and Narciclasine by Chemical Dearomatization of Bromobenzene
Southgate.HE, et al.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 129(47), 15245-15248 (2017)
K Conway et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 74(1), 20-26 (1999-04-06)
Chemical dehydration can be accomplished using 2,2-dimethoxypropane (DMP). In the presence of an acid catalyst, this liquid reacts with water generating methanol and acetone as products. Although DMP is more expensive per milliliter than ethanol and other solvents used for
H Halbritter
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 73(3), 137-143 (1998-07-23)
A simple, quick, and inexpensive method for preparing any type of pollen material is described. Fresh, mature pollen grains without previous chemical fixation are dehydrated in acidified 2, 2-dimethoxypropane (DMP) followed by critical-point drying in CO2. This method helps preserve
Vladimir A Khripach et al.
Steroids, 75(1), 27-33 (2009-09-30)
Preparation of partially protected brassinosteroids is achieved through the reaction of the source material (24-epicastasterone and 24-epibrassinolide) with diol-specific reagents (2,2-dimethoxypropane and methylboronic acid). The obtained products were shown to be useful synthetic intermediates for further preparation of minor representatives

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