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Merck
CN

74309

二甲氨苯酸辛酯

analytical standard

别名:

4-(二甲氨基)苯甲酸-2-乙基己酯

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线性分子式:
(CH3)2NC6H4CO2CH2CH(C2H5)(CH2)3CH3
化学文摘社编号:
分子量:
277.40
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
244-289-3
MDL number:
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InChI key

WYWZRNAHINYAEF-UHFFFAOYSA-N

InChI

1S/C17H27NO2/c1-5-7-8-14(6-2)13-20-17(19)15-9-11-16(12-10-15)18(3)4/h9-12,14H,5-8,13H2,1-4H3

SMILES string

CCCCC(CC)COC(=O)c1ccc(cc1)N(C)C

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.541±0.001, n20/D 1.542 (lit.)

bp

325 °C (lit.)

density

0.995 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

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General description

Padimate O is a tertiary amine derivative of p-aminobenzoic acid (PABA), which is commonly used as a sunscreen agent in cosmetics and other sunscreen formulations due to its ability to absorb ultraviolet radiations.

Application

Padimate O may be used as a reference standard in the determination of padimate O in cosmetics using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

374.0 °F - closed cup

flash_point_c

190 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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In vitro skin absorption and metabolism of Padimate-O and a nitrosamine formed in Padimate-O-containing cosmetic products.
Kenney EG, et al.
Journal of Society of Cosmetic Chemists of Japan, 46(2), 117-117 (1995)
Assay of mixtures of padimate-O and oxybenzone in sunscreen formulations by high-performance liquid chromatography.
Tan ISH, et al.
Journal of Chromatography A, 291, 275-282 (1984)
J A Johnson et al.
Dermatology (Basel, Switzerland), 185(4), 237-241 (1992-01-01)
Since window glass absorbs sunlight below 320 nm, it provides a means of assessing sensitivity to longer wavelengths, i.e. UVA and visible radiation. Positive responses to the query of whether symptoms develop in the auto with the windows up must
T M Morgan et al.
Journal of pharmaceutical sciences, 87(10), 1226-1228 (1998-10-06)
The objective of this study was to determine if a novel metered-dose topical aerosol (MDTA) formulation containing the new dermal penetration enhancer, padimate O, could enhance the transdermal delivery of estradiol to an extent that would result in clinically relevant
Gamal M M El Maghraby et al.
International journal of pharmaceutics, 305(1-2), 90-104 (2005-10-04)
Employing thermal analysis, we investigated the mechanism of action of novel enhancers and probed phospholipid (PL) versus stratum corneum lipid (SCL) liposomes as model membranes. The enhancers included octyl salicylate (OS), padimate O (PADO) and 2-(1-nonyl)-1,3-dioxolane (ND). The negative controls

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