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Merck
CN

74711

赭曲霉毒素A

purum, ≥98.0% (TLC), from Aspergillus ochraceus

别名:

N-[(3R)-(5-氯-8-羟基-3-甲基-1-氧代-7-异苯并二氢吡喃基)羰基]-L-苯丙氨酸

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关于此项目

经验公式(希尔记法):
C20H18ClNO6
化学文摘社编号:
分子量:
403.81
EC Number:
206-143-7
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1301486
MDL number:
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biological source

Aspergillus ochraceus

grade

purum

assay

≥98.0% (TLC)

form

powder

mode of action

enzyme | inhibits, protein synthesis | interferes

storage temp.

2-8°C

SMILES string

C[C@@H]1Cc2c(Cl)cc(c(O)c2C(=O)O1)C(=O)N[C@@H](Cc3ccccc3)C(O)=O

InChI

1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1

InChI key

RWQKHEORZBHNRI-BMIGLBTASA-N

Other Notes

Inhibitor of mitochondrial transport systems; Mode of action.


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R. Roschenthaler et al.
J. Toxicol.-Toxin Reviews, 3, 53-53 (1984)
Ochratoxin A, an inhibitor of mitochondrial transport systems.
H Meisner et al.
Biochemistry, 13(14), 2795-2800 (1974-07-02)
Fiorenza Minervini et al.
Toxins, 5(1), 84-92 (2013-01-25)
Ochratoxin A (OTA) is a renal mycotoxin and transplacental genotoxic carcinogen. The aim of this study was to evaluate the natural occurrence of OTA in equine blood samples and its placental transfer. For the assessment of OTA levels, serum samples