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Merck
CN

75412

Supelco

番泻苷 B

analytical standard

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关于此项目

经验公式（希尔记法）:
C42H38O20
化学文摘社编号:
128-57-4
分子量:
862.74
Beilstein:
5723747
EC 号:
204-895-0
MDL编号:
MFCD00151528
UNSPSC代码:
85151701
PubChem化学物质编号:
329766399
NACRES:
NA.24

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等级

analytical standard

质量水平

100

方案

≥90.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤10.0% water

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(cc(O)c8C(=O)c23)C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42?/m1/s1

InChI key

IPQVTOJGNYVQEO-OVYIKYHGSA-N

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一般描述

Sennoside B is a plant-derived anthranoid and is one of the active constituents of the senna drug. It is primarily used as a laxative and cathartic for treating constipation and bowel evacuation.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sennoside B may be used as a reference standard for the determination of sennoside B in pharmaceutical formulations by high-performance liquid chromatography method.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCJ0623
BCCH9047
BCCH4726
BCCG9026
BCCG2630

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Stimulant laxatives and opioid-induced constipation.
Twycross R, et al.
Journal of Pain and Symptom Management, 43(2), 306-313 (2012)
Validated HPLC method for determination of sennosides A and B in senna tablets.
Sun SW and Su HT
Journal of Pharmaceutical and Biomedical Analysis, 29(5), 881-894 (2002)
Jing Xiao et al.
Wei sheng yan jiu = Journal of hygiene research, 40(3), 355-357 (2011-06-24)
To develop an analytical method for determination of sennoside A and sennoside B simultaneously in health food by high performance liquid chromatography (HPLC). Samples were extracted by ultrasound extraction and determined by HPLC with a UV detector. Using a Synergi
Emi Matsui et al.
Biological & pharmaceutical bulletin, 34(9), 1438-1442 (2011-09-02)
Daiokanzoto (DKT), a Kampo medicine that includes the combination of two crude drugs (rhubarb and glycyrrhiza), is clinically effective for constipation. The aim of this study is to clarify the influence of glycyrrhiza, three glycyrrhiza constituents (glycyrrhizin, liquiritin, and liquiritin
Huifang Li et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(3), 302-304 (2012-05-10)
To determine the difference on purgative biopotency of different processed products of rhubarb and compare rhubarb before and after preparation. The prime biopotency of rhubarb reference substance was determined by comparing with the control substance of sennoside B using rat
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