77947
4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid
analytical standard
别名:
4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetic acid, Atenolol acid, Metoprolol acid
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关于此项目
经验公式(希尔记法):
C14H21NO4
化学文摘社编号:
分子量:
267.32
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥97.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CC(C)NCC(O)COc1ccc(CC(O)=O)cc1
InChI
1S/C14H21NO4/c1-10(2)15-8-12(16)9-19-13-5-3-11(4-6-13)7-14(17)18/h3-6,10,12,15-16H,7-9H2,1-2H3,(H,17,18)
InChI key
PUQIRTNPJRFRCZ-UHFFFAOYSA-N
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一般描述
4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid is a metabolite of the selective β-1 blocker drug metoprolol.
应用
4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid may be used as an analytical standard for the determination of the analyte in environmental water samples, wastewater samples, and human and animal biological samples by various chromatography techniques.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Development and Validation of RP-HPLC and an Ecofriendly HPTLC Method for Simultaneous Determination of Felodipine and Metoprolol Succinate, and their Major Metabolites in Human Spiked Plasma
Emam AA, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 809(1), 9-14 (2020)
Determination of metoprolol, and its four metabolites in dog plasma
Fang J, et al.
Journal of Chromatography. B, Biomedical Applications, 809(1), 9-14 (2004)
Fate of pharmaceuticals and their transformation products in integrated membrane systems for wastewater reclamation
Mamo J, et al.
Chemical Engineering Journal, 331, 450-461 (2018)
The
Small Animal Clinical Pharmacology, 241, 484-493 (2011)
Investigation of pharmaceuticals and their metabolites in Brazilian hospital wastewater by LC-QTOF MS screening combined with a preliminary exposure and in silico risk assessment
Becker RW, et al.
The Science of the Total Environment, 699, 134218-134218 (2020)
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