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Merck
CN

78697

甲基磺酸甲酯

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

别名:

甲磺酸甲酯

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关于此项目

线性分子式:
CH3SO3CH3
化学文摘社编号:
66-27-3
分子量:
110.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329768176
EC Number:
200-625-0
Beilstein/REAXYS Number:
1098586
MDL number:
MFCD00007557

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产品名称

甲基磺酸甲酯, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

InChI

1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3

InChI key

MBABOKRGFJTBAE-UHFFFAOYSA-N

SMILES string

COS(C)(=O)=O

grade

certified reference material
TraceCERT®

product line

TraceCERT®

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.414 (lit.)

bp

202-203 °C (lit.)

density

1.3 g/mL at 25 °C (lit.)

application(s)

environmental
pharmaceutical

format

neat

storage temp.

2-8°C

Quality Level

300

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相关类别

Application

有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
甲磺酸甲酯可用作认证标准物质，用于通过气相色谱-三重四级杆质谱联用法定量检测药物制剂中的分析物。

Biochem/physiol Actions

DNA 加合物；优先地将甲基加合到 DNA 的 7-鸟嘌呤，也可加合到 3-腺嘌呤和 3-鸟嘌呤。

General description

该认证标准物质（CRM）根据ISO/IEC 17025和ISO 17034进行生产和认证。该CRM可追溯来自NMI的原始材料，如NIST或NMIJ。NMR定量信息已包括在认证内容中。证书上已给出不确定性和失效日期。请在http://www.sigma-aldrich.com下载您的证书。

甲磺酸甲酯属于烷基磺酸酯类，是潜在的基因毒性杂质 (GTI)。

Other Notes

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Inhalation

target_organs

Lungs

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

分析证书(COA)

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Cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions induced in DNA and RNA in vitro and in pre-damaged DNA and RNA bacteriophages in vivo are repaired by the Escherichia coli (E. coli) protein AlkB and a human homolog, ALKBH3. However, it
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The Saccharomyces cerevisiae Shu complex, consisting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown mechanism. Recent structural analysis of two Shu proteins, Csm2 and Psy3, has revealed that these proteins are Rad51 paralogues and
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Molecular and cellular biology, 33(8), 1515-1527 (2013-02-06)
Cells employ error-free or error-prone postreplication repair (PRR) processes to tolerate DNA damage. Here, we present a genome-wide screen for sensitivity to 0.001% methyl methanesulfonate (MMS). This relatively low dose is of particular interest because wild-type cells exhibit no discernible
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