79593
(−)-Bilobalide
analytical standard
别名:
Bilobalide
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关于此项目
经验公式（希尔记法）:
C15H18O8
CAS Number:
分子量:
326.30
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥96.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
food and beverages
包装形式
neat
储存温度
2-8°C
SMILES字符串
CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)C[C@]23C(=O)O[C@@H]4OC(=O)[C@H](O)C134
InChI
1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13+,14+,15?/m0/s1
InChI key
MOLPUWBMSBJXER-DXPZGIEZSA-N
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相关类别
一般描述
(−)-Bilobalide is a Ginkgo terpenoid, available as the main pharmacological component in Ginkgo biloba extract. It exhibits neuroprotectant activity.
应用
(−)-Bilobalide may be used as an analytical rstandard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
This compound is commonly found in plants of the genus: ginkgo
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats
Xie J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 87-94 (2008)
LC-ESI-MS determination of bilobalide and ginkgolides in canine plasma
Tang J, et al.
Chromatographia, 63(1-2), 53-58 (2006)
Leige Ma et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(1), 89-96 (2012-10-23)
With various constituents in ginkgo biloba extract, the detailed internal mechanism underlying a reduction in anxiety and improvements to learning and memory from GBE is not well understood. The present study investigated whether bilobalide, an important constituent in GBE, could
Jiangang Shen et al.
Chinese medicine, 6, 8-8 (2011-02-25)
EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from ischemia-reperfusion injury. The present study aims to determine the effects of
Dorothee Lang et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 13(4), 607-614 (2010-01-01)
PURPOSE. Bilobalide is an active constituent of Ginkgo biloba and has shown neuroprotective effects in mice with cerebral ischemia. In the present study, we investigated brain permeability of bilobalide (i) in healthy mice and (ii) in mice before or after
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