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Merck
CN

79593

(−)-Bilobalide

analytical standard

别名:

Bilobalide

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关于此项目

经验公式(希尔记法):
C15H18O8
化学文摘社编号:
分子量:
326.30
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥96.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)C[C@]23C(=O)O[C@@H]4OC(=O)[C@H](O)C134

InChI

1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13+,14+,15?/m0/s1

InChI key

MOLPUWBMSBJXER-DXPZGIEZSA-N

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相关类别

一般描述

(−)-Bilobalide is a Ginkgo terpenoid, available as the main pharmacological component in Ginkgo biloba extract. It exhibits neuroprotectant activity.

应用

(−)-Bilobalide may be used as an analytical rstandard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

This compound is commonly found in plants of the genus: ginkgo

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

LC-ESI-MS determination of bilobalide and ginkgolides in canine plasma
Tang J, et al.
Chromatographia, 63(1-2), 53-58 (2006)
Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats
Xie J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 87-94 (2008)
Jiangang Shen et al.
Chinese medicine, 6, 8-8 (2011-02-25)
EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from ischemia-reperfusion injury. The present study aims to determine the effects of
Etsuko Suzuki et al.
The journal of physiological sciences : JPS, 61(5), 421-427 (2011-06-29)
Bilobalide, a unique constituent of Ginkgo biloba, has been reported to potentiate population spikes in hippocampal CA1 pyramidal cells and to protect the brain against cell death. In this study, the effects of bilobalide on synaptic transmission and its plasticity
Karin Woelkart et al.
Phytotherapy research : PTR, 24(3), 445-450 (2009-12-31)
A sensitive LC-ESI-MS method with a solid-phase extraction was established for the determination of bilobalide, ginkgolide A and ginkgolide B in human plasma; bioavailability and pharmacokinetics of three different Ginkgo biloba L. preparations have been investigated. The preparations used in

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