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线性分子式:
C6H5CH(OH)COC6H5
化学文摘社编号:
分子量:
212.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
204-331-3
Beilstein/REAXYS Number:
391839
MDL number:
InChI
1S/C14H12O2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13,15H
InChI key
ISAOCJYIOMOJEB-UHFFFAOYSA-N
SMILES string
OC(c1ccccc1)C(=O)c2ccccc2
grade
analytical standard
assay
≥99.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
bp
194 °C/12 mmHg (lit.)
mp
134-138 °C (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
format
neat
Quality Level
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General description
Benzoins are a class of 2-hydroxy ketones that are important subunits of several biologically active compounds.
Application
Benzoin has been used as a reference standard for the analysis of benzoin as an analyte protectant in fruit and vegetable samples by gas chromatography-mass spectrometry (GC-MS) operating in selected ion monitoring (SIM) mode. It may be used as a derivatizing agent for:
- Guanidino compounds in serum prior to their determination by micellar electrokinetic capillary (MEKC) chromatography (MEKC).
- Metformin in pharmaceutical preparations and urine prior to its determination by spectrophotometry.
- Famotidine and ranitidine in drugs and biological samples prior to their determination using high performance liquid chromatography-diode array detection (HPLC-DAD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Spectrophotometric determination of metformin in pharmaceutical preparations, serum and urine using benzoin as derivatizing reagent.
Alamgir M, et al.
J. Chem. Soc. Pak., 36(2), 344-349 (2014)
Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase.
Demir AS, et al.
Tetrahedron Asymmetry, 10(24), 4769-4774 (1999)
Evaluation of analyte protectants to improve gas chromatographic analysis of pesticides.
Anastassiades M, et al.
Journal of Chromatography A, 1015(1-2), 163-184 (2003)
HPLC Determination of Metformin, Famotidine and Ranitidine by Derivatization with Benzoin from Drugs and Biological Samples.
Alamgir MYKM, et al.
Pharmaceutica Analytica Acta, 8(546), 2-2 (2017)
Determination of guanidino compounds in serum by micellar electrokinetic capillary chromatography using benzoin as the derivatizing reagent.
Kandhro AJ, et al.
Analytical Letters, 43(13), 2049-2060 (2010)
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